关键词: COVID‐19 Hong Kong SARS‐CoV‐2 omicron variant disease transmission serial infection interval

Mesh : Humans COVID-19 / epidemiology Hong Kong / epidemiology SARS-CoV-2 / genetics Contact Tracing

来  源:   DOI:10.1111/irv.13105   PDF(Pubmed)

Abstract:
Empirical evidence on the epidemiological characteristics of the emerged SARS-CoV-2 variants could shed light on the transmission potential of the virus and strategic outbreak control planning. In this study, by using contact tracing data collected during an Omicron-predominant epidemic phase in Hong Kong, we estimated the mean serial interval of SARS-CoV-2 Omicron BA.4, BA.5, and BA.2.12.1 variants at 2.8 days (95% credible interval [CrI]: 1.5, 6.7), 2.7 days (95% CrI: 2.1, 3.6), and 4.4 days (95% CrI: 2.6, 7.5), respectively, with adjustment for right truncation and sampling bias. The short serial interval for the current circulating variant indicated that outbreak mitigations through contact tracing and case isolation would be quite challenging.
摘要:
关于出现的SARS-CoV-2变体的流行病学特征的经验证据可以揭示该病毒的传播潜力和战略暴发控制计划。在这项研究中,通过使用在香港以Omicron为主的流行阶段收集的接触者追踪数据,我们估计了SARS-CoV-2OmicronBA.4,BA.5和BA.2.12.1变体在2.8天的平均连续间隔(95%可信间隔[CrI]:1.5,6.7),2.7天(95%CrI:2.1,3.6),和4.4天(95%CrI:2.6,7.5),分别,调整右截断和采样偏差。当前流行变体的短序列间隔表明,通过接触者追踪和病例隔离来缓解爆发将是相当具有挑战性的。
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