Contact Tracing

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  • 文章类型: Journal Article
    研究动物社会系统需要了解接触和互动的变化,受环境条件等因素的影响,资源可用性,和捕食风险。传统的观测方法有其局限性,但是传感器技术和数据分析的进步提供了新的机会。我们开发了一种无线可穿戴传感器系统,\"Juxta,“具有模块化电池组和用于数据收集的智能手机应用程序等功能。对自由生活的草原田鼠(Microtusochogaster)的初步研究,一个具有复杂社会行为的物种,展示了Juxta研究社交网络和行为的潜力。我们提出了一个合并时间的框架,空间,和事件驱动的数据,这可以帮助探索跨物种和环境的复杂社会动态。
    Studying animal social systems requires understanding variations in contact and interaction, influenced by factors like environmental conditions, resource availability, and predation risk. Traditional observational methods have limitations, but advancements in sensor technologies and data analytics provide new opportunities. We developed a wireless wearable sensor system, \"Juxta,\" with features such as modular battery packs and a smartphone app for data collection. A pilot study on free-living prairie voles (Microtus ochrogaster), a species with complex social behavior, demonstrated Juxta\'s potential for studying social networks and behavior. We propose a framework for merging temporal, spatial, and event-driven data, which can help explore complex social dynamics across species and environments.
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  • 文章类型: Journal Article
    背景:接触者追踪是与其他预防措施协同实施的公共卫生干预措施,以遏制流行病,就像冠状病毒大流行一样。在世界范围内,数字设备的开发和使用已经增加,以增强接触追踪过程。该研究的目的是评估使用数字解决方案跟踪2019年冠状病毒病(COVID-19)患者的有效性和影响。
    方法:关于数字接触追踪(DCT)的观察性研究,发表于2020-21年,通过在9个在线数据库上进行的系统文献综述,以英语进行了鉴定。临时表格用于相关信息的数据提取。使用经过验证的工具对纳入研究进行质量评估。报告了这些发现的定性综合。
    结果:超过8000条记录被确定,37条被纳入研究:24项建模研究和13项基于人群的研究。DCT提高了COVID-19病例密切接触者的识别,并将COVID-19相关感染和死亡的有效繁殖数量减少了60%以上。它对社会和经济成本产生了积极影响,在封锁和资源使用方面,包括人员配备。27项研究报告了隐私和安全问题。
    结论:DCT有助于遏制COVID-19大流行,特别是设备的高吸收率以及其他公共卫生措施的结合,尤其是传统的接触追踪。装置实施的主要障碍是吸收率,安全和隐私问题。公共卫生数字化和接触者追踪是各国为未来卫生危机做好应急准备的关键。
    BACKGROUND: Contact tracing is a public health intervention implemented in synergy with other preventive measures to curb epidemics, like the coronavirus pandemic. The development and use of digital devices have increased worldwide to enhance the contact tracing process. The aim of the study was to evaluate the effectiveness and impact of tracking coronavirus disease 2019 (COVID-19) patients using digital solutions.
    METHODS: Observational studies on digital contact tracing (DCT), published 2020-21, in English were identified through a systematic literature review performed on nine online databases. An ad hoc form was used for data extraction of relevant information. Quality assessment of the included studies was performed with validated tools. A qualitative synthesis of the findings is reported.
    RESULTS: Over 8000 records were identified and 37 were included in the study: 24 modelling and 13 population-based studies. DCT improved the identification of close contacts of COVID-19 cases and reduced the effective reproduction number of COVID-19-related infections and deaths by over 60%. It impacted positively on societal and economic costs, in terms of lockdowns and use of resources, including staffing. Privacy and security issues were reported in 27 studies.
    CONCLUSIONS: DCT contributed to curbing the COVID-19 pandemic, especially with the high uptake rate of the devices and in combination with other public health measures, especially conventional contact tracing. The main barriers to the implementation of the devices are uptake rate, security and privacy issues. Public health digitalization and contact tracing are the keys to countries\' emergency preparedness for future health crises.
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  • 文章类型: Journal Article
    背景:大流行的管理和准备比以往任何时候都更加需要,政府对从COVID-19大流行中学习的广泛兴趣,以确保循证感染预防和控制措施的可用性。接触者追踪是感染预防和控制的组成部分,有针对性地促进传动链的断裂,识别与感染者接触过的人,并向他们提供与测试有关的指导/建议,医疗建议和/或自我隔离。
    目的:本研究旨在提高我们对在医疗机构中使用接触者追踪技术的理解。这项研究旨在通过研究这些技术如何减轻医院感染的传播,为感染预防和控制领域做出贡献。最终,这项研究旨在提高医疗保健服务的质量和安全性。
    方法:进行了系统的文献综述,从2022年3月至9月在OvidSP平台上保存的数据库中检索了调查接触者追踪技术在医疗保健环境中使用的期刊文章,没有下限日期。
    结果:总计,检索和筛选了277项研究,14项研究最终纳入系统文献综述。大多数研究调查了接近传感技术,报告有希望的结果。然而,研究受到样本量小和混杂因素的限制,揭示接触者追踪技术仍处于起步阶段。必须投资研究和开发新的测试技术,以加强国家和国际接触者追踪能力。
    结论:本综述旨在为那些打算创建强大的监测系统和实施传染病报告协议的人做出贡献。
    BACKGROUND: Pandemic management and preparedness are more needed than ever before and there is widespread governmental interest in learning from the COVID-19 pandemic in order to ensure the availability of evidence-based Infection Prevention and Control measures. Contact tracing is integral to Infection Prevention and Control, facilitating breaks in the chain of transmission in a targeted way, identifying individuals who have come into contact with an infected person, and providing them with instruction/advice relating to testing, medical advice and/or self-isolation.
    OBJECTIVE: This study aims to improve our understanding of the use of contact tracing technologies in healthcare settings. This research seeks to contribute to the field of Infection Prevention and Control by investigating how these technologies can mitigate the spread of nosocomial infections. Ultimately, this study aims to improve the quality and safety of healthcare delivery.
    METHODS: A systematic literature review was conducted, and journal articles investigating the use of contact tracing technologies in healthcare settings were retrieved from databases held on the OvidSP platform between March and September 2022, with no date for a lower limit.
    RESULTS: In total, 277 studies were retrieved and screened, and 14 studies were finally included in the systematic literature review. Most studies investigated proximity sensing technologies, reporting promising results. However, studies were limited by small sample sizes and confounding factors, revealing contact tracing technologies remain at a nascent stage. Investment in research and development of new testing technologies is necessary to strengthen national and international contact tracing capabilities.
    CONCLUSIONS: This review aims to contribute to those who intend to create robust surveillance systems and implement infectious disease reporting protocols.
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  • 文章类型: Journal Article
    背景:在大流行情况下,数字接触者追踪(DCT)是评估感染风险并在感染时告知他人的有效方法。DCT应用程序可以支持旨在跟踪联系人的用户的信息收集和分析过程。然而,用户对DCT信息的使用意图和使用可能取决于联系人追踪的感知好处。虽然现有的研究已经检查了DCT的接受度,自动化相关的用户体验因素被忽视。
    目标:我们追求三个目标:(1)分析与自动化相关的用户体验如何(即,感知的可信度,可追溯性,和有用性)与用户对DCT应用程序的行为有关,(2)将这些影响与健康行为因素联系起来(即,威胁评估和道德义务),(3)收集有关用户需求的定性数据,以改善DCT通信。
    方法:在COVID-19大流行期间,使用基于网络的便利样本,从全国范围内分布的DCT应用程序的317名用户那里收集了数据。我们评估了与自动化相关的用户体验。此外,我们评估了DCT使用的威胁评估和道德义务,以估计预测使用意图的偏最小二乘结构方程模型。为了提供实际步骤来改善用户体验,我们调查了用户对通过应用程序改善信息交流的需求,并使用主题分析分析了他们的回答。
    结果:数据有效性和感知有用性显示出r=0.38(P<.001)的显着相关性,目标一致性和感知有用性相关,r=0.47(P<.001),结果诊断性和感知有用性有很强的相关性,r=0.56(P<.001)。此外,在主观信息处理意识和感知有用性之间观察到r=0.35(P<.001)的相关性,这表明与自动化相关的变化可能会影响DCT的感知效用。最后,感知有用性和使用意向之间存在r=0.47(P<.001)的中度正相关,突出用户体验变量与使用意图之间的联系。偏最小二乘结构方程模型解释了55.6%的使用意图方差,最强的直接预测指标是感知可信度(β=.54;P<.001),其次是道德义务(β=.22;P<.001)。根据定性数据,用户主要要求更详细的联系人信息(例如,联系的地点和时间)。他们还想分享信息(例如,他们是否戴着口罩),以提高风险计算的准确性和诊断性。
    结论:DCT应用程序的感知结果诊断对感知可信度和使用意图至关重要。通过为用户设计高诊断性,DCT应用程序可以提高他们对用户行为监管的支持,导致更高的可信性和在大流行情况下的使用。总的来说,与自动化相关的用户体验对使用意图的重要性高于一般的健康行为或体验。
    BACKGROUND: In pandemic situations, digital contact tracing (DCT) can be an effective way to assess one\'s risk of infection and inform others in case of infection. DCT apps can support the information gathering and analysis processes of users aiming to trace contacts. However, users\' use intention and use of DCT information may depend on the perceived benefits of contact tracing. While existing research has examined acceptance in DCT, automation-related user experience factors have been overlooked.
    OBJECTIVE: We pursued three goals: (1) to analyze how automation-related user experience (ie, perceived trustworthiness, traceability, and usefulness) relates to user behavior toward a DCT app, (2) to contextualize these effects with health behavior factors (ie, threat appraisal and moral obligation), and (3) to collect qualitative data on user demands for improved DCT communication.
    METHODS: Survey data were collected from 317 users of a nationwide-distributed DCT app during the COVID-19 pandemic after it had been in app stores for >1 year using a web-based convenience sample. We assessed automation-related user experience. In addition, we assessed threat appraisal and moral obligation regarding DCT use to estimate a partial least squares structural equation model predicting use intention. To provide practical steps to improve the user experience, we surveyed users\' needs for improved communication of information via the app and analyzed their responses using thematic analysis.
    RESULTS: Data validity and perceived usefulness showed a significant correlation of r=0.38 (P<.001), goal congruity and perceived usefulness correlated at r=0.47 (P<.001), and result diagnosticity and perceived usefulness had a strong correlation of r=0.56 (P<.001). In addition, a correlation of r=0.35 (P<.001) was observed between Subjective Information Processing Awareness and perceived usefulness, suggesting that automation-related changes might influence the perceived utility of DCT. Finally, a moderate positive correlation of r=0.47 (P<.001) was found between perceived usefulness and use intention, highlighting the connection between user experience variables and use intention. Partial least squares structural equation modeling explained 55.6% of the variance in use intention, with the strongest direct predictor being perceived trustworthiness (β=.54; P<.001) followed by moral obligation (β=.22; P<.001). Based on the qualitative data, users mainly demanded more detailed information about contacts (eg, place and time of contact). They also wanted to share information (eg, whether they wore a mask) to improve the accuracy and diagnosticity of risk calculation.
    CONCLUSIONS: The perceived result diagnosticity of DCT apps is crucial for perceived trustworthiness and use intention. By designing for high diagnosticity for the user, DCT apps could improve their support in the action regulation of users, resulting in higher perceived trustworthiness and use in pandemic situations. In general, automation-related user experience has greater importance for use intention than general health behavior or experience.
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  • 文章类型: Journal Article
    我们计算了日本SARS-CoV-2OmicronBA.2主导时期COVID-19患者家庭接触者的攻击率。在近期(<3个月)未接种疫苗的家庭接触者中,完全接种疫苗的接触者的攻击率低于未完全接种疫苗的接触者。证明间接疫苗的有效性。
    We calculated attack rates for household contacts of COVID-19 patients during the SARS-CoV-2 Omicron BA.2-dominant period in Japan. Attack rates among household contacts without recent (<3 months) vaccination was lower for contacts of index patients with complete vaccination than for contacts of index patients without complete vaccination, demonstrating indirect vaccine effectiveness.
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  • 文章类型: Journal Article
    我们考虑网络上的SEIR流行病模型,也允许随机联系,康复的人可以自然康复或被诊断出来。诊断后,触发手动联系人跟踪,以便报告每个受感染的网络联系人,在随机延迟后,以一定的概率进行测试和隔离。此外,如果被诊断的个人是应用程序用户,则会触发数字跟踪(基于跟踪应用程序),然后立即通知并隔离所有使用其应用程序的感染者。具有手动和/或数字跟踪的流行病的早期阶段由不同的多类型分支过程来近似,并导出三个相应的再现数。通过减少繁殖次数,可以对两种接触追踪机制的有效性进行数字量化。这表明应用程序使用分数在接触者追踪的整体效果中起着至关重要的作用。与数字跟踪相比,手动跟踪的相对有效性增加,如果:更多的传输发生在网络上,当跟踪延迟缩短时,当网络度分布为重尾时。对于现实的价值观,组合跟踪案例可将R0降低20%-30%,因此,需要采取其他预防措施,将接触者追踪的繁殖数量减少到1.2-1.4,以成功避免大规模爆发。
    We consider an SEIR epidemic model on a network also allowing random contacts, where recovered individuals could either recover naturally or be diagnosed. Upon diagnosis, manual contact tracing is triggered such that each infected network contact is reported, tested and isolated with some probability and after a random delay. Additionally, digital tracing (based on a tracing app) is triggered if the diagnosed individual is an app-user, and then all of its app-using infectees are immediately notified and isolated. The early phase of the epidemic with manual and/or digital tracing is approximated by different multi-type branching processes, and three respective reproduction numbers are derived. The effectiveness of both contact tracing mechanisms is numerically quantified through the reduction of the reproduction number. This shows that app-using fraction plays an essential role in the overall effectiveness of contact tracing. The relative effectiveness of manual tracing compared to digital tracing increases if: more of the transmission occurs on the network, when the tracing delay is shortened, and when the network degree distribution is heavy-tailed. For realistic values, the combined tracing case can reduce R0 by 20%-30%, so other preventive measures are needed to reduce the reproduction number down to 1.2-1.4 for contact tracing to make it successful in avoiding big outbreaks.
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  • 文章类型: Journal Article
    本文使用来自韩国流行病学数据的感染网络对COVID-19传播动态进行了全面分析,涵盖2020年1月3日至2021年7月11日期间。该网络说明了感染者与感染者的关系,并为管理和减轻疾病的传播提供了宝贵的见解。然而,大量缺失的数据阻碍了流行病学监测对此类网络的常规分析。
    为了应对这一挑战,这篇文章提出了一种将个体分为四个不同群体的新方法,根据所有确诊病例中的感染者或感染者身份分类为追踪或未追踪病例。该研究分析了五个不同时期未追踪和追踪病例中感染网络的变化。
    四种类型的案例强调各种因素的影响,例如公共卫生战略的实施和新型COVID-19变种的出现,这有助于COVID-19传播的传播。其中一个关键发现是在特定年龄组中识别出显著的传播模式,特别是在20-29岁、40-69岁和0-9岁的人群中,基于四种类型的分类。此外,我们开发了一种新的实时指标来更有效地评估传染病传播的可能性。通过分析连接组件的长度,这一指标有助于改进预测,并使政策制定者能够积极应对,从而有助于减轻大流行对全球社区的影响。
    这项研究提供了一种对COVID-19病例进行分类的新方法,提供了对传播模式的见解,并引入了一个实时指标,以更好地评估和管理疾病传播,从而支持更有效的公共卫生干预措施。
    UNASSIGNED: This paper presents a comprehensive analysis of COVID-19 transmission dynamics using an infection network derived from epidemiological data in South Korea, covering the period from January 3, 2020, to July 11, 2021. The network illustrates infector-infectee relationships and provides invaluable insights for managing and mitigating the spread of the disease. However, significant missing data hinder conventional analysis of such networks from epidemiological surveillance.
    UNASSIGNED: To address this challenge, this article suggests a novel approach for categorizing individuals into four distinct groups, based on the classification of their infector or infectee status as either traced or untraced cases among all confirmed cases. The study analyzes the changes in the infection networks among untraced and traced cases across five distinct periods.
    UNASSIGNED: The four types of cases emphasize the impact of various factors, such as the implementation of public health strategies and the emergence of novel COVID-19 variants, which contribute to the propagation of COVID-19 transmission. One of the key findings is the identification of notable transmission patterns in specific age groups, particularly in those aged 20-29, 40-69, and 0-9, based on the four type classifications. Furthermore, we develop a novel real-time indicator to assess the potential for infectious disease transmission more effectively. By analyzing the lengths of connected components, this indicator facilitates improved predictions and enables policymakers to proactively respond, thereby helping to mitigate the effects of the pandemic on global communities.
    UNASSIGNED: This study offers a novel approach to categorizing COVID-19 cases, provides insights into transmission patterns, and introduces a real-time indicator for better assessment and management of the disease transmission, thereby supporting more effective public health interventions.
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  • 文章类型: Journal Article
    人口较少(例如,医院,学校或工作场所)的特征是高度接触异质性和随机性会影响病原体传播动力学。经验的个人接触数据提供了前所未有的信息来表征这种异质性,并且越来越容易获得,但通常在有限的时间内收集,并且可能遭受观察偏差。我们提出了一种算法,可以从医疗机构(HCS)中的个人联系人数据中随机重建现实的时间网络,并使用先前在长期护理机构(LTCF)中收集的真实数据来测试这种方法。我们的算法从记录的近距离交互生成完整的网络,使用每小时的个人间接触率和个人病房信息,接触人员的类别,以及反复接触的频率。它还通过在某些个人存在于HCS中而没有在经验数据中记录联系人的情况下重建几天的联系人来提供数据增强。记录偏差通过观察模型形式化,允许在增强网络和观察网络之间进行直接比较。我们使用i-Bird研究期间收集的数据验证了我们的算法,并比较经验网络和重构网络。该算法比随机图更准确地再现网络特征。重建的网络很好地再现了病房的多样性(观察到的第一至第三四分位数:0.54-0.64;合成:0.52-0.64)以及每小时的工作人员和患者接触模式。重要的是,观察到的时间相关性也得到了很好的再现(0.39-0.50vs0.37-0.44),表明我们的算法可以重建一个真实的时间结构。该算法一致地重新创建未观察到的接触以生成用于LTCF的完整的重构网络。最后,我们提出了一种方法来生成现实的时间接触网络,并从使用个体级交互网络计算的汇总统计数据中重建未观察到的接触。这可以应用和扩展到使用有限的经验数据生成其他HCS的接触网络,随后为基于个人的流行病模型提供信息。
    Small populations (e.g., hospitals, schools or workplaces) are characterised by high contact heterogeneity and stochasticity affecting pathogen transmission dynamics. Empirical individual contact data provide unprecedented information to characterize such heterogeneity and are increasingly available, but are usually collected over a limited period, and can suffer from observation bias. We propose an algorithm to stochastically reconstruct realistic temporal networks from individual contact data in healthcare settings (HCS) and test this approach using real data previously collected in a long-term care facility (LTCF). Our algorithm generates full networks from recorded close-proximity interactions, using hourly inter-individual contact rates and information on individuals\' wards, the categories of staff involved in contacts, and the frequency of recurring contacts. It also provides data augmentation by reconstructing contacts for days when some individuals are present in the HCS without having contacts recorded in the empirical data. Recording bias is formalized through an observation model, to allow direct comparison between the augmented and observed networks. We validate our algorithm using data collected during the i-Bird study, and compare the empirical and reconstructed networks. The algorithm was substantially more accurate to reproduce network characteristics than random graphs. The reconstructed networks reproduced well the assortativity by ward (first-third quartiles observed: 0.54-0.64; synthetic: 0.52-0.64) and the hourly staff and patient contact patterns. Importantly, the observed temporal correlation was also well reproduced (0.39-0.50 vs 0.37-0.44), indicating that our algorithm could recreate a realistic temporal structure. The algorithm consistently recreated unobserved contacts to generate full reconstructed networks for the LTCF. To conclude, we propose an approach to generate realistic temporal contact networks and reconstruct unobserved contacts from summary statistics computed using individual-level interaction networks. This could be applied and extended to generate contact networks to other HCS using limited empirical data, to subsequently inform individual-based epidemic models.
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  • 文章类型: Journal Article
    通过我们的呼吸系统,许多病毒和疾病经常从一个人传播到另一个人。Covid-19就是一个例子,说明追踪和减少接触以阻止其传播是多么重要。在寻找能够在复杂的城市场景或室内检测到面对面接触的自动方法方面存在明显差距。在本文中,我们介绍了一个计算机视觉框架,叫做FaceTouch,基于深度学习。它包括深度子模型来检测人类并分析他们的行为。FaceTouch试图检测野外的面对面触摸,例如通过视频聊天,巴士镜头,或闭路电视供稿。尽管面部部分遮挡,引入的系统通过利用诸如手臂运动的身体姿势的表示来学习从给定场景的RGB表示检测面部触摸。这已被证明在复杂的城市场景中很有用,除了简单地识别手部运动及其与面部的亲密关系。依靠监督对比学习,引入的模型是在我们收集的数据集上训练的,鉴于缺乏其他基准数据集。该框架在看不见的数据集中显示了强大的验证,为潜在的部署打开了大门。
    Through our respiratory system, many viruses and diseases frequently spread and pass from one person to another. Covid-19 served as an example of how crucial it is to track down and cut back on contacts to stop its spread. There is a clear gap in finding automatic methods that can detect hand-to-face contact in complex urban scenes or indoors. In this paper, we introduce a computer vision framework, called FaceTouch, based on deep learning. It comprises deep sub-models to detect humans and analyse their actions. FaceTouch seeks to detect hand-to-face touches in the wild, such as through video chats, bus footage, or CCTV feeds. Despite partial occlusion of faces, the introduced system learns to detect face touches from the RGB representation of a given scene by utilising the representation of the body gestures such as arm movement. This has been demonstrated to be useful in complex urban scenarios beyond simply identifying hand movement and its closeness to faces. Relying on Supervised Contrastive Learning, the introduced model is trained on our collected dataset, given the absence of other benchmark datasets. The framework shows a strong validation in unseen datasets which opens the door for potential deployment.
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  • 文章类型: Journal Article
    马来西亚的结核病(TB)接触者接受后续筛查,以降低其活动性或潜伏性TB的风险。然而,对这种筛查的依从性很低。有限的研究探讨了导致不坚持随访筛查的因素。这项研究旨在确定政府卫生诊所的不依从率和原因。
    参与者是因进行第二次接触筛查的结核病接触者(包括从2018年11月至2019年3月在PetraJaya健康诊所参加首次接触筛查的人)。年龄至少18岁,能够理解英语或马来语。数据是在2019年8月至2020年1月的第二次接触筛查期间收集的。
    共包括383个TB联系人。其中,56.6%(n=217)的年龄为20-39岁,性别分布相等(男性:44.1%,n=169)。大多数是非家庭接触者(82.2%,n=315)。随访筛查不依从率为19.1%(n=73)。大约52.1%(n=36)报告忘记了他们的预定预约日期是不遵守的主要原因。影响因素包括就业和种族。只有39.1%(n=27)知道他们患活动性结核病的风险。49.5%(n=189)不确定结核病是否可以通过适当的治疗治愈。
    调查结果强调了改进结核病联系人提醒系统的必要性。虽然知识和坚持之间的直接联系无法建立,与结核病相关的大多数基础知识问题的正确答案比例较低,这表明需要改善结核病接触者的健康教育.
    UNASSIGNED: Tuberculosis (TB) contacts in Malaysia undergo follow-up screening to reduce their risk of active or latent TB. However, adherence to this screening is low. Limited studies have explored the factors contributing to non-adherence to follow-up screening. This study aimed to determine the non-adherence rate and reasons in a government health clinic.
    UNASSIGNED: Participants were TB contacts due for their 2nd contact screening (including those who attended their first contact screening at Petra Jaya Health Clinic from November 2018 to March 2019), were aged at least 18 years and were able to understand English or Malay. Data were collected during the second contact screening from August 2019 to January 2020.
    UNASSIGNED: A total of 383 TB contacts were included. Of them, 56.6% (n=217) were aged 20-39 years, and the sex distribution was equal (men: 44.1%, n=169). The majority were non-household contacts (82.2%, n=315). The rate of non-adherence to follow-up screening was 19.1% (n=73). Approximately 52.1% (n=36) reported forgetting their scheduled appointment date as the primary reason for non-adherence. The influencing factors included employment and ethnicity. Only 39.1% (n=27) were aware of their risk for active TB, while 49.5% (n=189) were unsure whether TB can be cured with proper treatment.
    UNASSIGNED: The findings highlight the need to improve the reminder system for TB contacts. Although direct association between knowledge and adherence could not be established, the low percentage of correct answers to most basic knowledge questions associated with TB indicates a need to improve health education for TB contacts.
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