Abstract：
UNASSIGNED: Hypertensive disorders of pregnancy (HDP) is associated with an increased risk of adverse outcomes. The fetal middle cerebral artery (MCA) and umbilical artery (UA) blood flow detected by ultrasound are recommended to evaluate the oxygenation of the fetus. It is necessary to analyze the relationship between MCA & UA doppler indices or cerebroplacental ratio (CPR) and fetal outcomes and describe MCA and UA blood flow values across gestation.
UNASSIGNED: Hospital-based retrospective case-control study during 2016 to 2020. 800 singleton pregnant women: 400 normotensive control, 219 gestational hypertension (GH), and 181 preeclampsia (PE)/eclampsia (EC). An analysis of the outcomes of mothers and neonates was performed. The fetal MCA and UA blood flow values across gestation were established, and MCA-resistance index (RI) and CPR were used to predict fetal distress and small for gestational age (SGA).
UNASSIGNED: In the normotensive control, GH and PE/EC groups, the mean gestational age (GA) was 38.9 ± 1.2 weeks, 39.0 ± 1.0 weeks, and 38.6 ± 1.3 weeks respectively, and the mean birth weight (BW) was 3.195 ± 0.387 kilograms, 3.198 ± 0.428 kilograms, and 2.987 ± 0.544 kilograms respectively. There were differences in GA, BW, fetal distress, SGA and intraventricular hemorrhage I-II between the hypertension group and normotensive control group (p < 0.05). The MCA-RI (sensitivity: 70.1%, specificity: 64.3%) and MCA-RI (sensitivity: 52.4%, specificity: 84.6%) were the best indices to predict fetal distress and SGA, respectively during GA of 35-40 weeks.
UNASSIGNED: Fetal MCA blood flow values and CPR are of great benefit for obstetricians to evaluate the status of fetus evidentially in singleton pregnancy.
UNASSIGNED: Hospital-based retrospective case-control study during 2016 to 2020. 800 singleton pregnant women: 400 normotensive control, 219 gestational hypertension (GH), and 181 preeclampsia (PE)/eclampsia (EC). An analysis of the outcomes of mothers and neonates was performed. The fetal MCA and UA blood flow values across gestation were established, and MCA-resistance index (RI) and CPR were used to predict fetal distress and small for gestational age (SGA).
UNASSIGNED: In the normotensive control, GH and PE/EC groups, the mean gestational age (GA) was 38.9 ± 1.2 weeks, 39.0 ± 1.0 weeks, and 38.6 ± 1.3 weeks respectively, and the mean birth weight (BW) was 3.195 ± 0.387 kilograms, 3.198 ± 0.428 kilograms, and 2.987 ± 0.544 kilograms respectively. There were differences in GA, BW, fetal distress, SGA and intraventricular hemorrhage I-II between the hypertension group and normotensive control group (p < 0.05). The MCA-RI (sensitivity: 70.1%, specificity: 64.3%) and MCA-RI (sensitivity: 52.4%, specificity: 84.6%) were the best indices to predict fetal distress and SGA, respectively during GA of 35-40 weeks.
UNASSIGNED: Fetal MCA blood flow values and CPR are of great benefit for obstetricians to evaluate the status of fetus evidentially in singleton pregnancy.
摘要：
未经证实：妊娠高血压疾病（HDP）与不良结局的风险增加有关。建议通过超声检测胎儿大脑中动脉（MCA）和脐动脉（UA）血流来评估胎儿的氧合。有必要分析MCA和UA多普勒指数或脑胎盘比率（CPR）与胎儿结局之间的关系，并描述整个妊娠期的MCA和UA血流值。
UNASSIGNED：2016年至2020年期间以医院为基础的回顾性病例对照研究。800名单身孕妇：400名正常血压控制，219妊娠期高血压（GH），和181先兆子痫（PE）/子痫（EC）。对母亲和新生儿的结局进行了分析。建立了整个妊娠期的胎儿MCA和UA血流值，MCA抵抗指数（RI）和CPR用于预测胎儿窘迫和小于胎龄儿（SGA）。
未经评估：在正常血压控制中，GH和PE/EC组，平均胎龄（GA）为38.9±1.2周，39.0±1.0周，和38.6±1.3周，平均出生体重(BW)为3.195±0.387公斤，3.198±0.428公斤，和2.987±0.544公斤。GA有差异，BW,胎儿窘迫,高血压组与正常血压对照组之间的SGA和脑室内出血I-II（p<0.05）。MCA-RI（灵敏度：70.1%，特异性：64.3%）和MCA-RI（敏感性：52.4%，特异性：84.6%）是预测胎儿窘迫和SGA的最佳指标，分别在35-40周的GA期间。
UNASSIGNED：胎儿MCA血流量值和CPR对于产科医生在单胎妊娠中评估胎儿状况非常有益。
UNASSIGNED：2016年至2020年期间以医院为基础的回顾性病例对照研究。
未经评估：在正常血压控制中，
UNASSIGNED：胎儿MCA血流量值和CPR对于产科医生在单胎妊娠中评估胎儿状况非常有益。
