Abstract：
Although there is some evidence regarding an association between maternal bonding disorder and child development, studies have mainly focused on development during the period of infancy. We aimed to examine the associations between maternal postnatal bonding disorder and developmental delays in children beyond 2 years of age. We analyzed data from 8380 mother-child pairs who participated in the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Maternal bonding disorder was defined as Mother-to-Infant Bonding Scale score of ≥5 at 1 month after delivery. The Ages & Stages Questionnaires, Third Edition, which consists of five developmental areas, was used to assess developmental delays in children at 2 and 3.5 years of age. Multiple logistic regression analyses were conducted to examine the associations between postnatal bonding disorder and developmental delays after adjustment for age, education, income, parity, feelings toward pregnancy, postnatal depressive symptoms, child\'s sex, preterm birth, and birth defects. Bonding disorder was associated with developmental delays in children at 2 and 3.5 years of age: the odds ratios (95% confidence intervals) were 1.55 (1.32-1.83) and 1.60 (1.34-1.90), respectively. Bonding disorder was associated with delay in communication only at 3.5 years of age. Bonding disorder was associated with delay in gross motor, fine motor, and problem solving, but not delay in the personal-social domain, at 2 and 3.5 years of age. In conclusion, maternal bonding disorder 1 month after delivery was associated with an increased risk of developmental delays in children beyond 2 years of age.
摘要：
尽管有一些证据表明母系结合障碍与儿童发育之间存在关联，研究主要集中在婴儿期的发展。我们旨在研究2岁以上儿童的母亲产后结合障碍与发育迟缓之间的关系。我们分析了参加东北医学超级银行项目出生和三代队列研究的8380对母子对的数据。产妇粘结障碍定义为分娩后1个月母婴粘结量表评分≥5。年龄和阶段问卷调查，第三版,由五个发展领域组成，用于评估2岁和3.5岁儿童的发育迟缓。进行了多逻辑回归分析，以检查出生后结合障碍和年龄调整后发育迟缓之间的关联。教育,收入,奇偶校验，对怀孕的感觉，产后抑郁症状,孩子的性，早产,出生缺陷。粘结障碍与2岁和3.5岁儿童的发育迟缓有关：比值比（95％置信区间）为1.55（1.32-1.83）和1.60（1.34-1.90），分别。粘结障碍仅在3.5岁时与沟通延迟有关。粘结障碍与粗大运动延迟有关，精细电机，解决问题，但不要拖延个人社会领域，2岁和3.5岁。总之,分娩后1个月母系结合障碍与2岁以上儿童的发育迟缓风险增加相关.
