Abstract：
Evaluation of a candidate for hematopoietic cell transplantation (HCT) is a complex process with substantial intercenter variability. Although literature providing guidance for evaluating the eligibility of adults is well established, similar guidance for children is lacking. To address gaps between adult recommendations and the specific needs of children, we convened a panel of pediatric HCT experts from a wide geographic range of American Society of Transplantation and Cellular Therapy (ASTCT) member institutions to offer recommendations for pediatric-focused pre-HCT evaluation. In this report from the ASTCT Committee on Practice Guidelines, we present a practical framework for evaluating children with malignancies who are candidates for HCT. We also highlight key differences from adults and emphasize areas of unmet need that require additional research to delineate best practices.
摘要：
造血细胞移植（HCT）候选者的评估是一个复杂的过程，具有明显的中心间变异性。尽管为评估成年人的资格提供指导的文献已经确立，缺乏对儿童的类似指导。为了解决成人建议与儿童具体需求之间的差距，我们召集了一组来自美国移植和细胞治疗协会(ASTCT)成员机构的儿科HCT专家,以提供以儿科为重点的HCT前评估建议.在ASTCT实践准则委员会的这份报告中，我们提出了一个实用的框架,用于评估适合HCT的恶性肿瘤儿童.我们还强调了与成年人的主要差异，并强调了需要进一步研究以描绘最佳实践的未满足需求的领域。
