PDF(Pubmed)
Abstract：
An 86-year-old woman with a subcutaneous nodule in her left axilla visited our hospital. She had no gastrointestinal symptoms, but contrast-enhanced computed tomography revealed a cecal mass and systemic metastasis, including cutaneous, bone, peritoneal dissemination and ascites. Colonoscopy revealed a circumferential, elevated cecal lesion. She underwent right hemicolectomy to prevent colon obstruction. The pathological diagnosis was poorly differentiated adenocarcinoma (por1>tub2>muc) arising from the appendix with a BRAFV600E mutation and microsatellite instability-high. Chemotherapy was administered, and she is currently still alive and undergoing chemotherapy. We describe a rare case of advanced appendiceal cancer without gastrointestinal symptoms diagnosed due to cutaneous metastasis.
摘要：
一名86岁的妇女，左腋下有皮下结节。她没有胃肠道症状,但对比增强计算机断层扫描显示盲肠肿块和全身转移，包括皮肤,骨头,腹膜播散和腹水。结肠镜检查显示，盲肠病变升高。她接受了右半结肠切除术以防止结肠梗阻。病理诊断为阑尾引起的低分化腺癌（por1>tub2>muc），具有BRAFV600E突变和微卫星不稳定性高。进行了化疗，她目前还活着，正在接受化疗。我们描述了一例因皮肤转移而没有胃肠道症状的晚期阑尾癌的罕见病例。
