Abstract：
Background Magnetoencephalography (MEG) and electroencephalography (EEG) record two main types of data: continuous measurements at rest or during sleep, and event-related potentials/evoked magnetic fields (ERPs/EMFs) that involve specific and repetitive tasks. In this systematic review, we summarized longitudinal studies on recovery from post-stroke aphasia that used continuous or event-related temporal imaging (EEG or MEG). Methods We searched PubMed and Scopus for English articles published from 1950 to May 31, 2022. Results 34 studies were included in this review: 11 were non-interventional studies and 23 were clinical trials that used specific rehabilitation methods, neuromodulation, or drugs. The results of the non-interventional studies suggested that poor language recovery was associated with slow-wave activity persisting over time. The results of some clinical trials indicated that behavioral improvements were correlated with significant modulation of the N400 component. Discussion Compared with continuous EEG, ERP/EMF may more reliably identify biomarkers of therapy-induced effects. Electrophysiology should be used more often to explore language processes that are impaired after a stroke, as it may highlight treatment challenges for patients with post-stroke aphasia.
摘要：
背景脑磁图（MEG）和脑电图（EEG）记录了两种主要类型的数据：休息或睡眠期间的连续测量，和事件相关电位/诱发磁场（ERP/EMFs），涉及特定和重复的任务。在这次系统审查中，我们总结了使用连续或事件相关时间成像(EEG或MEG)的卒中后失语症恢复的纵向研究.方法我们搜索了PubMed和Scopus从1950年到2022年5月31日发表的英文文章。结果本综述共纳入34项研究：11项为非干预性研究，23项为使用特定康复方法的临床试验，神经调节,或药物。非干预性研究的结果表明，语言恢复不良与随时间持续的慢波活动有关。一些临床试验的结果表明，行为改善与N400成分的显着调节相关。讨论与连续脑电图相比，ERP/EMF可以更可靠地识别治疗诱导效应的生物标志物。应该更经常地使用电生理学来探索中风后受损的语言过程，因为它可能突出了卒中后失语症患者的治疗挑战.
