Abstract：
It has been suggested that domestic animals can serve as sentinels for human exposures. In this study our objectives were to demonstrate that i) silicone collars can be used to measure environmental exposures of (domestic) animals, and that ii) domestic animals can be used as sentinels for human residential exposure. For this, we simultaneously measured polycyclic aromatic hydrocarbons (PAHs) using silicone bands worn by 30 pet cats (collar) and their owner (wristband). Collars and wristbands were worn for 7 days and analyzed via targeted Gas Chromatography-Mass Spectrometry (GC-MS). Demographics and daily routines were collected for humans and cats. Out of 16 PAHs, 9 were frequently detected (>50% of samples) in both wristbands and collars, of which Phenanthrene and Fluorene were detected in all samples. Concentrations of wristbands and collars were moderately correlated for these 9 PAHs (Median Spearman\'s r = 0.51 (range 0.16-0.68)). Determinants of PAH concentrations of cats and humans showed considerable overlap, with vacuum cleaning resulting in higher exposures and frequent changing of bed sheets in lower exposures. This study adds proof-of-principle data for the use of silicone collars to measure (domestic) animal exposure and shows that cats can be used as sentinels for human residential exposure.
摘要：
有人建议，家畜可以作为人类暴露的哨兵。在这项研究中，我们的目标是证明i）硅胶项圈可用于测量（家畜）动物的环境暴露，以及ii）家畜可以用作人类居住暴露的哨兵。为此，我们使用30只宠物猫（项圈）及其主人（腕带）佩戴的硅胶带同时测量多环芳烃（PAHs）。将项圈和腕带佩戴7天,并通过靶向气相色谱-质谱(GC-MS)进行分析。收集人和猫的人口统计学和日常生活。在16种PAHs中,在腕带和项圈中经常检测到9个（>50％的样本），其中在所有样品中都检测到菲和芴。腕带和项圈的浓度与这9种PAHs中度相关（中值Spearman\'sr=0.51（范围0.16-0.68））。猫和人的PAH浓度的决定因素显示出相当大的重叠，真空清洁导致较高的曝光和频繁更换床单在较低的曝光。这项研究增加了使用硅胶项圈测量（家养）动物暴露的原理证明数据，并表明猫可以用作人类住宅暴露的哨兵。
