Abstract：
Many studies have proven the relationship between air pollutants and respiratory diseases, but few studies have assessed the impacts of air particulate matter exposure on older patients with pneumonia. This study aimed to reveal the impacts of short-term exposure to air particulate matter on the daily number of older adult patients hospitalized due to pneumonia and calculate the economic costs attributable to this exposure. We collected inpatient data from 9 city hospitals in Sichuan Province, China, from January 1, 2018, to December 31, 2019, and calculated odds ratios and 95% confidence intervals using a time-stratified case-crossover study design and an attributable risk model to calculate the economic burden due to particulate matter pollution. It was found that for every 10 μg/m3 increase in PM2.5 and PM10 concentrations, the daily number of older adult pneumonia inpatients increased by 1.5% (95% CI: 1.010-1.021) and 1.0% (95% CI: 1.006-1.014), respectively. Those 65 ~ 79 years old were more susceptible to air particulate pollutants (P < 0.05). During the study period, the total hospitalization costs and out-of-pocket expenses attributable to PM2.5 and PM10 exposure were 44.60 million CNY (6.22%) and 16.03 million CNY (6.21%), respectively, with PM2.5 being the primary influencing factor. This study revealed the relationship between particulate matter pollution and pneumonia among older adults. The role of policies to limit particulate matter concentrations in reducing disease burden among older adults can be further explored.
摘要：
许多研究证明了空气污染物与呼吸系统疾病之间的关系，但很少有研究评估空气颗粒物暴露对老年肺炎患者的影响。这项研究旨在揭示短期暴露于空气颗粒物对因肺炎住院的老年患者每日人数的影响，并计算可归因于这种暴露的经济成本。我们收集了四川省9家城市医院的住院数据，中国,从2018年1月1日至2019年12月31日,使用时间分层病例交叉研究设计和归因风险模型计算颗粒物污染造成的经济负担,计算比值比和95%置信区间.发现PM2.5和PM10浓度每增加10μg/m3，老年人肺炎的每日住院人数增加了1.5%（95%CI：1.010-1.021）和1.0%（95%CI：1.006-1.014），分别。65~79岁人群更容易受到大气颗粒物污染物的影响(P<0.05)。在学习期间,因PM2.5和PM10暴露引起的住院总费用和自付费用分别为4460万元人民币（6.22%）和1603万元人民币（6.21%），分别,PM2.5是主要影响因素。这项研究揭示了老年人中颗粒物污染与肺炎之间的关系。可以进一步探讨限制颗粒物浓度的政策在减少老年人疾病负担中的作用。
