肝硬化患者的肌肉减少症 : 当前知识和未来方向。
关键词: ACE, angiotensin-converting enzyme ACE-I, angiotensin-converting enzyme inhibitor AKI, acute kidney injury ALM, appendicular lean mass ARB, angiotensin receptor blocker ASM, appendicular skeletal mass AT1R, angiotensin type 1 receptor AT2R, angiotensin type 2 receptor ATP, adenosine-5′-triphosphate AWGS, Asian Working Group for Sarcopenia BCAA, branched chained amino acids BIA, bioelectrical impedance analysis BMI, body mass index CART, classification and regression tree CKD, chronic kidney disease CRP, C-reactive protein DEXA, dual energy X-ray absorptiometry EAA, essential amino acids ESPEN-SIG, European Society for Clinical Nutrition and Metabolism Special Interests Groups ESRD, end-stage renal disease EWGSOP, European Working Group on Sarcopenia in Older People FAD, flavin adenine dinucleotide FADH2, flavin adenine dinucleotide +2 hydrogen FNIH, Foundation for the National Institutes of Health GTP, guanosine-5′-triphosphate GnRH, gonadotrophin-releasing hormone HCC, hepatocellular carcinoma HPT, hypothalamic-pituitary-testicular IFN-γ, interferon γ IGF-1, insulin-like growth factor 1 IL-1, interleukin-1 IL-6, interleukin-6 IWGS, International Working Group on Sarcopenia LH, luteinizing hormone MELD, Model for End-Stage Liver Disease MuRF1, muscle RING-finger-1 NAD, nicotinamide adenine dinucleotide NADH, nicotinamide adenine dinucleotide + hydrogen NADPH, nicotinamide adenine dinucleotide phosphate NAFLD, non-alcoholic fatty liver disease NASH, non-alcoholic steatohepatitis NF-κβ, nuclear factor κβ NHANES, National Health and Nutritional Examination Survey PMI, psoas muscle index PMTH, psoas muscle thickness RAAS, renin-angiotensin-aldosterone system ROS, reactive oxygen species SARC-F, Strength, Assistance with walking, Rise from a chair, Climb stairs, and Falls SHBG, sex hormone binding globulin SMI, skeletal muscle index SNS, sympathetic nervous system SPPB, Short Performance Physical Battery TNF-α, tumor necrosis factor α UCSF, University of California, San Francisco UNOS, United Network of Organ Sharing cirrhosis energy mTOR, mammalian target of rapamycin metabolism muscle sarcopenia
来 源:
DOI:10.1016/j.jceh.2022.06.005
PDF(Pubmed)