Abstract：
In Asia, mulberry has long been used to treat various infectious and internal ailments as a traditional medication. The compounds found in it have the potential to improve human health. Because there is no approved and defined evaluation procedure, it has not been formally or scientifically recognized. As a result of these investigations, a new frontier in traditional Chinese medicine has opened up, with the possibility of modernization, for the interaction between active components of mulberry and their biological activities. These studies have used current biotechnological technologies. For ages, mulberry has been used as an herbal remedy in Asia to cure various diseases and internal disorders. It has a high concentration of bioactive chemicals that benefit human health. The most abundant phenolic components extracted from white mulberry leaves are flavonoids (Kuwanons, Moracinflavans, Moragrols, and Morkotins), phenolic acids, alkaloids, and so forth. Flavonoids, benzofurans, chalcones, and alkaloids have been discovered to have cytotoxic effects on human cancer cell lines. There is growing evidence that mulberry fruits can potentially prevent cancer and other aging-related disorders due to their high concentration of bioactive polyphenolic-rich compounds and macro and micronutrients. Anthocyanins are rapidly absorbed after eating, arriving in the plasmalemma within 15-50 min and entirely removed after 6-8 hr. Due to a lack of an approved and consistent technique for its examination, it has yet to be formally or scientifically recognized. The mulberry plant is commercially grown for silkworm rearing, and less attention is paid to its bioactive molecules, which have a lot of applications in human health. This review paper discusses the phenolic compounds of white mulberry and black mulberry in detail concerning their role in cancer prevention.
摘要：
在亚洲,桑树作为传统药物长期以来一直被用来治疗各种传染病和内部疾病。其中发现的化合物具有改善人类健康的潜力。由于没有批准和定义的评估程序，它尚未得到正式或科学的认可。由于这些调查，开辟了中医药的新领域，有了现代化的可能性，为桑树活性成分之间的相互作用及其生物活性。这些研究使用了当前的生物技术。对于年龄，桑树在亚洲已被用作治疗各种疾病和内部疾病的草药。它含有高浓度的生物活性化学物质，有益于人类健康。从白色桑叶中提取的最丰富的酚类成分是类黄酮(Kuwanons，Moracinflavans,Moragrols,和Morkotins)，酚酸，生物碱，等等。黄酮类化合物,苯并呋喃,查尔酮,和生物碱已被发现对人类癌细胞系具有细胞毒性作用。越来越多的证据表明，桑树果实由于其高浓度的富含生物活性多酚的化合物以及大量和微量营养素，可以潜在地预防癌症和其他与衰老相关的疾病。花青素在食用后迅速吸收，在15-50分钟内到达质膜，并在6-8小时后完全清除。由于缺乏认可和一致的检查技术，它尚未得到正式或科学认可。桑树植物是商业种植的，用于养蚕，对其生物活性分子的关注较少，在人类健康中有很多应用。本文详细讨论了白桑树和黑桑树的酚类化合物在预防癌症中的作用。
