Abstract：
BACKGROUND: Benign lymphoid hyperplasia (BLH) is a rare lymphoproliferative disorder of normal polyclonal B lymphocytes, but is sometimes difficult to distinguish from malignancy.
METHODS: An 87-year-old man with a history of localized non-small cell lung cancer (NSCLC) was referred for evaluation and treatment of an elastic hard tumor in the left supraclavicular fossa one year after stereotactic ablative radiotherapy (SABR). Whole-body PET scan showed high 18F-fluorodeoxyglucose uptake in the left supraclavicular fossa, and a dia-gnosis of oligometastasis was made. The tumor was homogeneously high signal on T2-weighted image with homogeneous enhancement after contrast administration. Since the palpation and MRI findings were inconsistent with those of metastatic NSCLC, a bio-psy was performed. Pathological and immunohistochemical investigation revealed the lesion to be BLH.
CONCLUSIONS: In a patient with suspected oligometastasis after SABR for NSCLC, caution should be exercised before undergoing SABR for oligometastasis because BLH may be present.
METHODS: An 87-year-old man with a history of localized non-small cell lung cancer (NSCLC) was referred for evaluation and treatment of an elastic hard tumor in the left supraclavicular fossa one year after stereotactic ablative radiotherapy (SABR). Whole-body PET scan showed high 18F-fluorodeoxyglucose uptake in the left supraclavicular fossa, and a dia-gnosis of oligometastasis was made. The tumor was homogeneously high signal on T2-weighted image with homogeneous enhancement after contrast administration. Since the palpation and MRI findings were inconsistent with those of metastatic NSCLC, a bio-psy was performed. Pathological and immunohistochemical investigation revealed the lesion to be BLH.
CONCLUSIONS: In a patient with suspected oligometastasis after SABR for NSCLC, caution should be exercised before undergoing SABR for oligometastasis because BLH may be present.
摘要：
背景：良性淋巴增生（BLH）是一种罕见的正常多克隆B淋巴细胞的淋巴增生性疾病，但有时很难区分恶性肿瘤。
方法：一名有局限性非小细胞肺癌（NSCLC）病史的87岁男性患者在立体定向消融放疗（SABR）一年后接受左锁骨上窝弹性硬肿瘤的评估和治疗。全身PET扫描显示左锁骨上窝摄取高18F-氟代脱氧葡萄糖，并对寡转移进行了诊断。在T2加权图像上，肿瘤呈均匀高信号，造影剂给药后均一增强。由于触诊和MRI结果与转移性NSCLC不一致，进行了生物检查。病理和免疫组织化学检查显示病变为BLH。
结论：在SABR治疗NSCLC后疑似寡转移的患者中，在进行SABR进行寡转移之前，应谨慎行事，因为可能存在BLH。
方法：一名有局限性非小细胞肺癌（NSCLC）病史的87岁男性患者在立体定向消融放疗（SABR）一年后接受左锁骨上窝弹性硬肿瘤的评估和治疗。全身PET扫描显示左锁骨上窝摄取高18F-氟代脱氧葡萄糖，并对寡转移进行了诊断。在T2加权图像上，肿瘤呈均匀高信号，造影剂给药后均一增强。由于触诊和MRI结果与转移性NSCLC不一致，进行了生物检查。病理和免疫组织化学检查显示病变为BLH。
结论：在SABR治疗NSCLC后疑似寡转移的患者中，在进行SABR进行寡转移之前，应谨慎行事，因为可能存在BLH。
