Abstract：
Rod-like graphite carbon nitride@MnO2 (R-g-C3N5@MnO2) heterostructure was prepared by in situ self-anchored growth of MnO2 nanosheet on the surface of R-g-C3N5. The synthesized R-g-C3N5@MnO2 heterostructure as photoactive material exhibited excellent photoelectrochemical (PEC) performance, and the prepared heterostructure-aptamer probe displayed sensitive PEC response to cTnI. Therefore, the PEC method was developed to detect cTnI based on the R-g-C3N5@MnO2 heterostructure. It was found that the linear response to cTnI was in the range 0.001-30 ng/mL under optimized conditions, and the detection limit of the proposed sensor was 0.3 pg/mL. The PEC method displays stable photocurrent response up to 8 cycles and exhibited outstanding selectivity and sensitivity. The PEC method was successfully applied to detect cTnI in serum samples. The recoveries of cTnI detection in serums reach 95.5-104%, and the relative standard deviations range from 3.20 to 4.45%.
摘要：
通过在R-g-C3N5表面原位自锚定生长MnO2纳米片，制备了棒状石墨碳氮化物@MnO2（R-g-C3N5@MnO2）异质结构。合成的R-g-C3N5@MnO2异质结构作为光活性材料表现出优异的光电化学(PEC)性能,制备的异质结构-适体探针对cTnI表现出敏感的PEC反应。因此,基于R-g-C3N5@MnO2异质结构，开发了PEC方法来检测cTnI。发现在优化条件下，对cTnI的线性响应在0.001-30ng/mL范围内，所提出的传感器的检出限为0.3pg/mL。PEC方法显示稳定的光电流响应长达8个循环，并表现出出色的选择性和灵敏度。PEC方法成功应用于血清样品中cTnI的检测。血清中cTnI检测的回收率达到95.5-104％，相对标准偏差范围为3.20~4.45%。
