%0 Journal Article
%T Photoelectrochemical determination of cardiac troponin I based on rod-like g-C3N5@MnO2 heterostructure.
%A Wang H
%A Lu Q
%A Luo J
%A Zeng X
%A Zhao C
%A Du F
%A Zhang Y
%A Zeng G
%A Zhang S
%J Mikrochim Acta
%V 190
%N 1
%D 12 2022 13
%M 36512092
%F 6.408
%R 10.1007/s00604-022-05547-4
%X Rod-like graphite carbon nitride@MnO2 (R-g-C3N5@MnO2) heterostructure was prepared by in situ self-anchored growth of MnO2 nanosheet on the surface of R-g-C3N5. The synthesized R-g-C3N5@MnO2 heterostructure as photoactive material exhibited excellent photoelectrochemical (PEC) performance, and the prepared heterostructure-aptamer probe displayed sensitive PEC response to cTnI. Therefore, the PEC method was developed to detect cTnI based on the R-g-C3N5@MnO2 heterostructure. It was found that the linear response to cTnI was in the range 0.001-30 ng/mL under optimized conditions, and the detection limit of the proposed sensor was 0.3 pg/mL. The PEC method displays stable photocurrent response up to 8 cycles and exhibited outstanding selectivity and sensitivity. The PEC method was successfully applied to detect cTnI in serum samples. The recoveries of cTnI detection in serums reach 95.5-104%, and the relative standard deviations range from 3.20 to 4.45%.