Abstract：
Background: The optimal timing of laser epilation with expanded forehead flaps in facial defect reconstruction remains undetermined. Objective: To compare the efficacy and safety of hair removal during or after flap expansion. Methods: This prospective exploratory study included 15 (11 women and 4 men, 16.47 ± 16.331 years of age) and 26 (19 women and 7 men, 10.69 ± 10.899 years of age) patients who underwent 755 nm long-pulsed alexandrite laser epilation during flap expansion and after surgery, respectively. Facial reconstruction was performed in these patients because of congenital melanin nevus, scar or port-wine stains. Evaluation included hair reduction rate, patient satisfaction, and adverse events. Results: The median number of laser sessions for hair removal during flap expansion was significantly lower than that after surgery (2.00 vs. 3.00, p < 0.01), and the hair reduction rate was also significantly higher during flap expansion (79.5% ± 21.93% vs. 68.3% ± 17.44%, p < 0.05). No severe adverse events were reported. Conclusion: Laser hair removal is safe and efficient when performed both during flap expansion period and after surgery, but its efficacy was significantly higher, and fewer sessions were required when performed during tissue expansion. Clinical trial registration information: ChiCTR1900026090.
摘要：
背景：在面部缺损重建中，使用扩张的前额皮瓣进行激光脱毛的最佳时机仍不确定。目的：比较皮瓣扩张过程中或后脱毛的疗效和安全性。方法：这项前瞻性探索性研究包括15名(11名女性和4名男性，16.47±16.331岁）和26（19名女性和7名男性，10.69±10.899岁）患者在皮瓣扩张过程中和手术后进行了755nm长脉冲翠绿宝石激光脱毛，分别。由于先天性黑色素痣，这些患者进行了面部重建，疤痕或葡萄酒污渍。评估包括脱发率，患者满意度,和不良事件。结果：皮瓣扩张过程中激光脱毛的中位次数明显低于手术后（2.00vs.3.00，p<0.01)，皮瓣扩张时的毛发减少率也明显更高(79.5%±21.93%vs.68.3%±17.44%,p<0.05)。未报告严重不良事件。结论：激光脱毛在皮瓣扩张期间和手术后都是安全有效的，但是它的功效明显更高，并且在组织扩张期间进行时需要较少的疗程。临床试验注册信息：ChiCTR1900026090。
