UNASSIGNED: We searched ISI Web of Science, Embase, PubMed, and the Cochrane Library. Our study included cohort studies reporting hazard ratio ( HR). The random-effects model was used for summarizing the total relative risks ( RRs) between the included studies. In addition, the generalized least-squares regression was employed to fit the study model.
UNASSIGNED: A total of 9 studies involving 645,006 participants were included in this study. A significant non-linear relationship was observed between sodium excretion and CV events ( P non-linearity < 0.001). In studies collecting 24-h urine samples, the sodium excretion and CV events risk were associated linearly ( RR: 1.04; 95% CI: 1.01, 1.07).
UNASSIGNED: In a linear dose-response manner, every 1 g increase in sodium intake was associated with an increased risk of CV events up to 4%. Further studies are required to validate our conclusions further.
未经批准:我们搜索了ISIWebofScience,Embase,PubMed,还有Cochrane图书馆.我们的研究包括报告风险比(HR)的队列研究。随机效应模型用于总结纳入研究之间的总相对风险(RR)。此外,采用广义最小二乘回归拟合研究模型.
UNASSIGNED:本研究共纳入9项研究,涉及645,006名参与者。在钠排泄和CV事件之间观察到显著的非线性关系(P非线性<0.001)。在收集24小时尿样的研究中,钠排泄和CV事件风险呈线性关系(RR:1.04;95%CI:1.01,1.07).
未经评估:以线性剂量反应方式,钠摄入量每增加1g,CV事件风险增加高达4%.需要进一步的研究来进一步验证我们的结论。