PDF(Pubmed)
Abstract：
Parkinsonism-hyperpyrexia syndrome (PHS) is a rare, potentially fatal neurological emergency, that is seen in Parkinson\'s Disease (PD) patients and mimics neuroleptic malignant syndrome. The most common trigger for PHS is sudden withdrawal of anti-parkinsonian medications, specifically levodopa. However, it can also be due to Deep Brain Stimulation (DBS) device malfunction. In this work, we describe three cases of PHS; the first of which is related to DBS battery depletion, and the remaining two to dopaminergic withdrawal. Additionally, we will include the results of a literature review on PHS, its etiologies, presentation, and management.
摘要：
帕金森综合征-高热综合征（PHS）是一种罕见的，可能致命的神经系统急症,这在帕金森病（PD）患者中可见，模拟了抗精神病药恶性综合征。小灵通最常见的诱因是突然停药，特别是左旋多巴。然而,它也可能是由于深部脑刺激（DBS）设备故障。在这项工作中,我们描述了三种情况的小灵通；第一种情况与DBS电池耗尽有关，剩下的两个是多巴胺能戒断。此外,我们将包括关于PHS的文献综述的结果，其病因，介绍,和管理。
