{Reference Type}: Case Reports
{Title}: Parkinsonism-Hyperpyrexia Syndrome: A Case Series and Literature Review.
{Author}: Azar J;Jaber Y;Ayyad M;Abu Alia W;Owda F;Sharabati H;Zeid H;Khreshi S;AlBandak M;Sayyed Ahmad D;
{Journal}: Cureus
{Volume}: 14
{Issue}: 9
{Year}: Sep 2022
暂无{DOI}: 10.7759/cureus.29646
{Abstract}: Parkinsonism-hyperpyrexia syndrome (PHS) is a rare, potentially fatal neurological emergency, that is seen in Parkinson's Disease (PD) patients and mimics neuroleptic malignant syndrome. The most common trigger for PHS is sudden withdrawal of anti-parkinsonian medications, specifically levodopa. However, it can also be due to Deep Brain Stimulation (DBS) device malfunction. In this work, we describe three cases of PHS; the first of which is related to DBS battery depletion, and the remaining two to dopaminergic withdrawal. Additionally, we will include the results of a literature review on PHS, its etiologies, presentation, and management.