%0 Case Reports
%T Parkinsonism-Hyperpyrexia Syndrome: A Case Series and Literature Review.
%A Azar J
%A Jaber Y
%A Ayyad M
%A Abu Alia W
%A Owda F
%A Sharabati H
%A Zeid H
%A Khreshi S
%A AlBandak M
%A Sayyed Ahmad D
%J Cureus
%V 14
%N 9
%D Sep 2022
%M 36320988
暂无%R 10.7759/cureus.29646
%X Parkinsonism-hyperpyrexia syndrome (PHS) is a rare, potentially fatal neurological emergency, that is seen in Parkinson's Disease (PD) patients and mimics neuroleptic malignant syndrome. The most common trigger for PHS is sudden withdrawal of anti-parkinsonian medications, specifically levodopa. However, it can also be due to Deep Brain Stimulation (DBS) device malfunction. In this work, we describe three cases of PHS; the first of which is related to DBS battery depletion, and the remaining two to dopaminergic withdrawal. Additionally, we will include the results of a literature review on PHS, its etiologies, presentation, and management.