Abstract：
Novel technologies and platforms have allowed significant breakthroughs in dental pulp tissue engineering. The development of injectable scaffolds that can be combined with stem cells, growth factors, or other bioactive compounds has enabled the regeneration of functional dental pulps able to secrete dentin in preclinical and clinical studies. Similarly, cell-homing technologies and scaffold-free strategies aim to modulate dental pulp self-regeneration mediated by resident stem cells and can evade some of the technical challenges related to cell-based tissue engineering strategies. This article will discuss emerging technologies and platforms for the clinical applications of dental pulp tissue engineering.
摘要：
新技术和平台使牙髓组织工程取得了重大突破。可与干细胞结合的可注射支架的开发，生长因子，或其他生物活性化合物使能够在临床前和临床研究中分泌牙本质的功能性牙髓再生。同样，细胞归巢技术和无支架策略旨在调节由常驻干细胞介导的牙髓自我再生，并且可以避免与基于细胞的组织工程策略相关的一些技术挑战。本文将讨论牙髓组织工程临床应用的新兴技术和平台。
