Abstract：
BACKGROUND: This study aimed to identify the epidemiology, seasonality, aetiology and clinical characteristics of sporadic foodborne diseases in Zhejiang province during 2016-2020.
METHODS: Descriptive statistical methods were used to analyze the data from surveillance network established by the Zhejiang Provincial Center for Disease Control and Prevention. There were 31 designated hospitals in all 11 cities which were selected using probability proportionate to size sampling method.
RESULTS: During the study period, the surveillance system received 75,124 cases with 4826 (6.42%) hospitalizations from 31 hospitals. The most common cause was Norovirus, 6120 cases (42.56%), followed by Salmonella, 3351 cases (23.30%). A significant seasonal trend was observed for the V. parahaemolyticus, with the highest rates over the summer period, peaking in August, 1171 cases (38.75%), a similar trend was also observed with Salmonella and Diarrheagenic E. coli. Norovirus infections showed the highest rate in November (904, 14.77%) and March (660,10.78%), the lowest in August, 215 cases (3.51%). Patients between 19 ~ 40 years were more likely to infected by Norovirus, V. parahaemolyticus and Diarrheagenic E. coli, patients below 1 year were the highest among patients with Salmonella infection, 881 cases (26.3%). The Norovirus, V. parahaemolyticus and Diarrheagenic E. coli infection with the highest positive detection rates among the workers were observed. The largest number cases of food categories were from aquatic product infection. The private home was the most common exposure setting.
CONCLUSIONS: Our study highlighted the necessity for conducting an active, comprehensive surveillance for pathogens in all age groups, to monitor the changing dynamics in the epidemiology and aetiology of foodborne diseases to guide policies that would reduce related illnesses.
METHODS: Descriptive statistical methods were used to analyze the data from surveillance network established by the Zhejiang Provincial Center for Disease Control and Prevention. There were 31 designated hospitals in all 11 cities which were selected using probability proportionate to size sampling method.
RESULTS: During the study period, the surveillance system received 75,124 cases with 4826 (6.42%) hospitalizations from 31 hospitals. The most common cause was Norovirus, 6120 cases (42.56%), followed by Salmonella, 3351 cases (23.30%). A significant seasonal trend was observed for the V. parahaemolyticus, with the highest rates over the summer period, peaking in August, 1171 cases (38.75%), a similar trend was also observed with Salmonella and Diarrheagenic E. coli. Norovirus infections showed the highest rate in November (904, 14.77%) and March (660,10.78%), the lowest in August, 215 cases (3.51%). Patients between 19 ~ 40 years were more likely to infected by Norovirus, V. parahaemolyticus and Diarrheagenic E. coli, patients below 1 year were the highest among patients with Salmonella infection, 881 cases (26.3%). The Norovirus, V. parahaemolyticus and Diarrheagenic E. coli infection with the highest positive detection rates among the workers were observed. The largest number cases of food categories were from aquatic product infection. The private home was the most common exposure setting.
CONCLUSIONS: Our study highlighted the necessity for conducting an active, comprehensive surveillance for pathogens in all age groups, to monitor the changing dynamics in the epidemiology and aetiology of foodborne diseases to guide policies that would reduce related illnesses.
摘要：
背景：本研究旨在确定流行病学，季节性,2016-2020年期间浙江省散发性食源性疾病的病因和临床特征。
方法：采用描述性统计方法对浙江省疾病预防控制中心建立的监测网络数据进行分析。在所有11个城市中，有31家指定医院是使用与规模成比例的概率抽样方法选择的。
结果：在研究期间，监测系统从31家医院接收了75,124例病例,其中4826例(6.42%)住院.最常见的原因是诺如病毒,6120例（42.56%），其次是沙门氏菌,3351例(23.30%)。副溶血性弧菌有明显的季节性趋势，夏季期间费率最高，在八月达到顶峰，1171例（38.75%），沙门氏菌和腹泻大肠杆菌也观察到了类似的趋势。诺如病毒感染率最高的是11月(904,14.77%)和3月(660,10.78%),8月最低,215例(3.51%)。19~40岁的患者更容易感染诺如病毒,五、副溶血性和腹泻性大肠杆菌，1岁以下的患者在沙门氏菌感染患者中最高，881例(26.3%)。诺如病毒,观察到工人中阳性检出率最高的副溶血性和腹泻性大肠杆菌感染。食品类别中最多的病例来自水产品感染。私人住宅是最常见的曝光环境。
结论：我们的研究强调了进行积极，对所有年龄组的病原体进行全面监测，监测食源性疾病的流行病学和病因的变化动态，以指导减少相关疾病的政策。
方法：采用描述性统计方法对浙江省疾病预防控制中心建立的监测网络数据进行分析。在所有11个城市中，有31家指定医院是使用与规模成比例的概率抽样方法选择的。
结果：在研究期间，监测系统从31家医院接收了75,124例病例,其中4826例(6.42%)住院.最常见的原因是诺如病毒,6120例（42.56%），其次是沙门氏菌,3351例(23.30%)。副溶血性弧菌有明显的季节性趋势，夏季期间费率最高，在八月达到顶峰，1171例（38.75%），沙门氏菌和腹泻大肠杆菌也观察到了类似的趋势。诺如病毒感染率最高的是11月(904,14.77%)和3月(660,10.78%),8月最低,215例(3.51%)。19~40岁的患者更容易感染诺如病毒,五、副溶血性和腹泻性大肠杆菌，1岁以下的患者在沙门氏菌感染患者中最高，881例(26.3%)。诺如病毒,观察到工人中阳性检出率最高的副溶血性和腹泻性大肠杆菌感染。食品类别中最多的病例来自水产品感染。私人住宅是最常见的曝光环境。
结论：我们的研究强调了进行积极，对所有年龄组的病原体进行全面监测，监测食源性疾病的流行病学和病因的变化动态，以指导减少相关疾病的政策。
