CT = computed tomography

CT = 计算机断层扫描
  • 文章类型: Journal Article
    背景:动脉瘤性骨囊肿(ABC)很少见,主要影响儿科人群的高度血管溶骨性骨病变。本报告评估了小儿脊髓ABCs患者的临床病理资料。评估了1998年至2018年间在洛杉矶儿童医院经活检证实的脊柱ABC的所有患者的病历。
    方法:17名患者,6男11女,已确定。手术的平均年龄为10.4岁(范围,3.5-20年)。最常见的主诉是病变部位疼痛16/17(94%),其次是下肢无力8/17(47%)。所有患者均进行了切除和病灶内刮治。17例患者中有3例(18%)在切除前进行了选择性动脉栓塞。17例患者中有15例(88%)脊柱稳定性受损,需要仪器融合。17例患者中有5例(29%)接受了包括放疗在内的额外治疗,降钙素-甲基强的松龙,或者苯酚。17例患者中有4例(23.5%)出现复发,平均复发时间为15个月。术后随访6~108个月(中位数,28个月)。平均35个月后再次手术。在最近的后续行动中,患者没有疾病。
    结论:通过病灶内刮除与病例相关的器械脊柱融合术治疗不稳定的大体全切除仍然是治疗小儿脊柱ABC的有效策略。长期随访对于检测肿瘤复发是必要的。
    BACKGROUND: Aneurysmal bone cysts (ABCs) are rare, highly vascular osteolytic bone lesions that predominantly affect pediatric populations. This report evaluates the clinicopathological data of pediatric patients with spinal ABCs. The medical records for all patients at Children\'s Hospital Los Angeles with biopsy-proven ABCs of the spine between 1998 and 2018 were evaluated.
    METHODS: Seventeen patients, 6 males and 11 females, were identified. The mean age at surgery was 10.4 years (range, 3.5-20 years). The most common presenting complaint was pain at the lesion site 16/17 (94%), followed by lower-extremity weakness 8/17 (47%). Resection and intralesional curettage were performed in all patients. Three (18%) of 17 patients underwent selective arterial embolization prior to resection. Spinal stability was compromised in 15 of 17 patients (88%), requiring instrumented fusion. Five (29%) of the 17 patients received additional therapy including radiation, calcitonin-methylprednisolone, or phenol. Four (23.5%) of 17 patients experienced a recurrence, and the mean time to recurrence was 15 months. The postoperative follow-up ranged from 6 to 108 months (median, 28 months). Reoperation occurred after an average of 35 months. At the recent follow-up, patients were free of disease.
    CONCLUSIONS: Gross-total resection by intralesional curettage with case-dependent instrumented spinal fusion for instability remains an effective strategy for managing pediatric spinal ABCs. Long-term follow-up is necessary to detect tumor recurrence.
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  • 文章类型: Journal Article
    背景:颅内和脊髓脑脊液(CSF)泄漏与相反的CSF流体动力学有关。自发性颅脑和脊髓脑脊液漏的不同病理生理学是,因此,理论上是相互排斥的。
    方法:一名66岁女性出现张力性气颅。患者接受了计算机断层扫描(CT)扫描,表现为左侧张力性气颅,在鼓膜和乳突的骨缺损正上方有大量的空气。患者接受了左中窝开颅手术,以修复tegmenCSF泄漏。出院后的一周,她出现了位置性头痛复发,并接受了头部CT检查。大脑和胸椎的进一步磁共振成像显示双侧硬膜下血肿和多发性脑膜憩室。
    结论:颅内脑脊液漏由颅内高压引起,与硬膜下血肿无关。每当发现“耳源性”气颅时,临床医生应保持对脊髓CSF渗漏引起的颅内低血压的高度怀疑。建议对任何接受耳源性气胸的tegmen缺损修复的患者进行密切的术后随访和临床监测,以了解颅内低血压的症状。
    Cranial and spinal cerebrospinal fluid (CSF) leaks are associated with opposite CSF fluid dynamics. The differing pathophysiology between spontaneous cranial and spinal CSF leaks are, therefore, mutually exclusive in theory.
    A 66-year-old female presented with tension pneumocephalus. The patient underwent computed tomography (CT) scanning, which demonstrated left-sided tension pneumocephalus, with an expanding volume of air directly above a bony defect of the tegmen tympani and mastoideum. The patient underwent a left middle fossa craniotomy for repair of the tegmen CSF leak. In the week after discharge, she developed a recurrence of positional headaches and underwent head CT. Further magnetic resonance imaging of the brain and thoracic spine showed bilateral subdural hematomas and multiple meningeal diverticula.
    Cranial CSF leaks are caused by intracranial hypertension and are not associated with subdural hematomas. Clinicians should maintain a high index of suspicion for intracranial hypotension due to spinal CSF leak whenever \"otogenic\" pneumocephalus is found. Close postoperative follow-up and clinical monitoring for symptoms of intracranial hypotension in any patients who undergo repair of a tegmen defect for otogenic pneumocephalus is recommended.
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  • 文章类型: Journal Article
    背景:Belonidae鱼科与各种穿透性损伤有关;迄今为止,然而,由于该物种造成的脑损伤的报道有限。
    方法:作者介绍了一名年轻患者的病例,该患者因针鱼导致眼穿透性损伤,导致海绵窦血栓形成并伴有颈动脉海绵窦瘘。该病例强调了通过抗凝滴定到瘘管闭合终点的策略对这种罕见疾病的跨学科管理。
    结论:通过本报告,强调了高度怀疑穿透性眼外伤中神经血管损伤和瘘形成的重要性,以及对此类损伤及其后遗症患者进行跨学科管理的重要性。
    BACKGROUND: The Belonidae family of fish has been implicated in various penetrating injuries; to date, however, there have been limited reports of brain injury due to this species.
    METHODS: The authors present the case of a young patient who suffered an ocular penetrating injury from a needlefish with a resultant cavernous sinus thrombosis and concomitant carotid-cavernous fistula. This case highlights the interdisciplinary management of this rare condition through a strategy of anticoagulation titration to the endpoint of fistula closure.
    CONCLUSIONS: Through this report the importance of a high index of suspicion for neurovascular injury and fistula formation in penetrating ocular injuries is highlighted as well as the importance of interdisciplinary management of patients with such injuries and their sequelae.
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  • 文章类型: Journal Article
    背景:作者报告了一例66岁男性,该男性急性出现硬膜下血肿,接受开颅手术治疗。他的病程因术后硬膜外血肿而变得复杂,which,根据第二次手术的术中发现,通过清除血肿和切除骨瓣来管理。
    方法:患者随后的恢复在术后早期表现为可再现的位置性失语症,最终诊断为环锯综合征。患者的脑水肿允许早期自体颅骨修补术,这导致了患者症状的解决。
    结论:作者认为该病例是第一个被描述为孤立性位置性失语症的表现。对该综合征的识别和治疗导致积极的患者结果。
    BACKGROUND: The authors report a case of a 66-year-old male who presented acutely with a subdural hematoma who was managed operatively with craniotomy. His course was complicated by a postoperative epidural hematoma, which, on the basis of intraoperative findings at the second surgery, was managed with evacuation of the hematoma and removal of the bone flap.
    METHODS: The patient\'s subsequent recovery was remarkable for a reproducible positional aphasia in the early postoperative period with an ultimate diagnosis of syndrome of the trephined. The patient\'s cerebral edema permitted early autologous cranioplasty, which resulted in resolution of the patient\'s symptoms.
    CONCLUSIONS: The authors believe this case to be the first described of isolated positional aphasia as a manifestation of syndrome of the trephined. Recognition and treatment of the syndrome resulted in a positive patient outcome.
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  • 文章类型: Journal Article
    背景:作者\'先前的尸体研究报告了一种新的手术方法,可以暴露小脑半球深处,小脑桥脑角,通过解剖枕下小脑半球的水平裂和上第四脑室。这里,作者介绍了他们的经验,首次临床使用枕下横裂(SOTHF)方法,需要进入第三和上第四脑室病变,通过传统方法进入一个具有挑战性的隔间。
    方法:在病例1和2中,计算机断层扫描显示左小脑半球有大量血肿,并延伸到第三脑室和/或第四脑室上部,导致梗阻性脑积水.仅通过SOTHF方法即可成功清除小脑半球和第四脑室上部的大血肿,而无需外部脑室引流。此外,在病例2中,第三脑室的血肿通过导水管清除。术中使用神经导航系统验证了对上第四脑室和第三脑室的访问。病人立刻恢复了意识,术后小脑功能测试结果基本正常。
    结论:SOTHF方法可以同时清除小脑和脑室内血肿,是一种比其他方法更快、更安全的方法,并随后允许快速的临床改善。
    BACKGROUND: The authors\' previous cadaveric study reported a new surgical approach that can expose the deep cerebellar hemisphere, cerebellopontine angle, and upper fourth ventricle through dissection of the horizontal fissure of the suboccipital cerebellar hemisphere. Here, the authors present their experience with the first clinical use of the suboccipital trans-horizontal fissure (SOTHF) approach requiring access to the third and upper fourth ventricle lesions, a challenging compartment to access by traditional approaches.
    METHODS: In cases 1 and 2, computed tomography demonstrated large hematomas in the left cerebellar hemisphere with extension into the third ventricle and/or the upper fourth ventricle, resulting in obstructive hydrocephalus. Large hematomas in both the cerebellar hemisphere and the upper fourth ventricle were successfully removed via an SOTHF approach alone without external ventricular drainage. Furthermore, the hematoma in the third ventricle was removed through the aqueduct in case 2. Access to the upper fourth ventricle and the third ventricle were intraoperatively verified using a neuronavigation system. The patients immediately regained consciousness, and the result of cerebellar function testing was almost normal after the operation.
    CONCLUSIONS: An SOTHF approach can achieve the removal of cerebellar and intraventricular hematomas simultaneously, is a faster and potentially safer method than others, and subsequently allows rapid clinical improvement.
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  • 文章类型: Case Reports
    背景:三柱截骨术导致硬脑膜屈曲,这可能在术中可视化时出现担忧,因为它可能看起来神经元也可能被弯曲。作者介绍了有意对神经元进行硬膜切开术后的术中视图以及三柱截骨后硬脑膜的松弛状态。
    方法:一名52岁女性,患有成人脊髓栓系综合征,以前没有栓系,腿部疼痛和僵硬加重,尿失禁,步态不平衡。磁共振成像显示T6和脊髓栓系有蛛网膜。通过三柱截骨术进行脊柱缩短,同时进行蛛网膜硬膜内切除。术中观察到脊柱缩短后硬脑膜屈曲。硬骨切开术后,可见脊髓没有扭结或屈曲。
    结论:在T6时通过三柱截骨术缩短15mm的脊柱后硬脑膜屈曲未导致基础神经元的屈曲。
    BACKGROUND: A three-column osteotomy results in dural buckling, which may appear concerning upon intraoperative visualization because it may appear that the neural elements may also be buckled. The authors presented an intraoperative view after intentional durotomy of the neural elements and the relaxed state of the dura after three-column osteotomy.
    METHODS: A 52-year-old woman with adult tethered cord syndrome and previous untethering presented with worsening leg pain and stiffness, urinary incontinence, and unbalanced gait. Magnetic resonance imaging demonstrated an arachnoid web at T6 and spinal cord tethering. Spinal column shortening via three-column osteotomy was performed with concomitant intradural excision of the arachnoid web. Dural buckling was observed intraoperatively after spinal column shortening. After the durotomy, the spinal cord was visualized without kinking or buckling.
    CONCLUSIONS: Dural buckling after spinal column shortening of 15 mm via three-column osteotomy at T6 did not result in concomitant buckling of the underlying neural elements.
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  • 文章类型: Case Reports
    背景:建立颅外至颅内高流量旁路后捕获动脉瘤被认为是治疗颈内动脉(ICA)破裂血泡样动脉瘤(BBA)的最佳手术策略。对于高流量旁路手术,桡动脉移植物通常优于隐静脉移植物(SVG)。然而,SVG在急性期手术中可能是有利的,因为它们的长度更大,易于操作,作为高流量管道的能力,降低血管痉挛的风险.在这项研究中,作者介绍了5例破裂的BBAs,使用SVG进行高流量旁路治疗,然后进行BBA捕获,他们报告了可能有助于避免潜在陷阱的手术结果和手术细微差别。
    方法:手术后,没有缺血或出血性并发症,包括有症状的血管痉挛.在五个案例中的三个,术后3个月随访时改良Rankin量表评分为0~2分.在一个案例中,手术后SVG自发闭塞,而保护颞浅动脉(STA)至大脑中动脉(MCA)旁路占优势,患者没有出现缺血症状。
    结论:使用SVG和保护性STA-MCA旁路,然后进行BBA捕获的高流量旁路是一种安全有效的治疗策略。
    BACKGROUND: Trapping an aneurysm after the establishment of an extracranial to intracranial high-flow bypass is considered the optimal surgical strategy for ruptured blood blister-like aneurysms (BBAs) of the internal carotid artery (ICA). For high-flow bypass surgeries, a radial artery graft is generally preferred over a saphenous vein graft (SVG). However, SVGs can be advantageous in acute-phase surgeries because of their greater length, easy manipulability, ability to act as high-flow conduits, and reduced risk of vasospasms. In this study, the authors presented five cases of ruptured BBAs treated with high-flow bypass using an SVG followed by BBA trapping, and they reported on surgical outcomes and operative nuances that may help avoid potential pitfalls.
    METHODS: After the surgeries, there were no ischemic or hemorrhagic complications, including symptomatic vasospasms. In three of the five cases, postoperative modified Rankin scale scores were between 0 and 2 at the 3-month follow-up. In one case, the SVG spontaneously occluded after surgery while the protective superficial temporal artery (STA) to middle cerebral artery (MCA) bypass became dominant, and the patient experienced no ischemic symptoms.
    CONCLUSIONS: High-flow bypass using an SVG with a protective STA-MCA bypass followed by BBA trapping is a safe and effective treatment strategy.
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  • 文章类型: Case Reports
    背景:中枢神经系统(CNS)结核瘤是结核病(TB)感染的可怕并发症。这些病变可以以不同的方式出现,并与显著的发病率和死亡率相关。在这些患者的护理中,及时诊断和治疗病变和潜在的感染至关重要。作者介绍了一例45岁的也门移民,有3个月的严重右颞枕头痛伴畏光和盗汗的病史。影像学显示右小脑半球有边缘增强病变。
    方法:实验室检查无异常且在正常范围内。Quantiferon检测结果为阴性,排除潜在的结核病感染。病人接受了枕下开颅手术,切除小脑病变显示干酪样肉芽肿形成,抗酸杆菌和Fite染色呈阳性。
    结论:中枢神经系统结核瘤是有原发性结核病史的患者需要考虑的重要差异,无论活动性疾病或免疫能力状态。切除这些病变仍然是安全有效的可行治疗选择。
    BACKGROUND: Central nervous system (CNS) tuberculomas are a feared complication of tuberculosis (TB) infection. These lesions can present in varying manners and are associated with significant morbidity and mortality. Prompt diagnosis and treatment of the lesion and the underlying infection are critical in the care of these patients. The authors presented a case of a 45-year-old Yemeni immigrant presenting with a 3-month history of severe right temporo-occipital headaches with photophobia and night sweats. Imaging showed a rim-enhancing lesion in the right cerebellar hemisphere.
    METHODS: Laboratory tests were unremarkable and within normal limits. QuantiFERON testing was negative, ruling out latent TB infection. The patient received a suboccipital craniotomy, and resection of the cerebellar lesion showed caseating granuloma formation, which was positive for acid-fast bacilli and Fite stain.
    CONCLUSIONS: CNS tuberculomas are an important differential to consider in patients with a history of primary TB, regardless of active disease or immunocompetent status. Resection of these lesions remains a viable treatment option that is safe and effective.
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  • 文章类型: Case Reports
    背景:解剖变异,例如高颈静脉球和岩骨中的空气细胞发育,应该在手术前进行评估。内耳道(IAC)后壁的大多数骨缺损都是在周围的细胞中观察到的。穿过岩骨的异常血管结构很少见。
    方法:一名48岁男性出现右耳听力障碍。磁共振成像显示右桥小脑角有23毫米的对比增强肿块延伸到IAC,与右前庭神经鞘瘤一致.术前骨窗计算机断层扫描显示IAC后壁骨缺损,在岩骨中向下延伸,到达颈静脉球的内侧部分。通过枕下侧入路进入肿瘤。小脑延髓池没有其他主要静脉,除了从脑干到IAC后壁的静脉。为了避免由于静脉充血引起的并发症,作者没有钻取IAC后壁或切除IAC中的肿瘤.
    结论:岩骨中的一些异常静脉是原始的头窦残留物。虽然罕见,它们的手术意义对于前庭神经鞘瘤患者至关重要。
    BACKGROUND: Anatomical variations, such as high jugular bulbs and air cell development in the petrosal bone, should be evaluated before surgery. Most bone defects in the internal auditory canal (IAC) posterior wall are observed in the perilabyrinthine cells. An aberrant vascular structure passing through the petrous bone is rare.
    METHODS: A 48-year-old man presented with a right ear hearing disturbance. Magnetic resonance imaging revealed a 23-mm contrast-enhancing mass in the right cerebellopontine angle extending into the IAC, consistent with a right vestibular schwannoma. Preoperative bone window computed tomographic scans showed bone defects in the IAC posterior wall, which ran farther posteroinferiorly in the petrous bone, reaching the medial part of the jugular bulb. The tumor was accessed via a lateral suboccipital approach. There was no other major vein in the cerebellomedullary cistern, except for the vein running from the brain stem to the IAC posterior wall. To avoid complications due to venous congestion, the authors did not drill out the IAC posterior wall or remove the tumor in the IAC.
    CONCLUSIONS: Several aberrant veins in the petrous bone are primitive head sinus remnants. Although rare, their surgical implication is critical in patients with vestibular schwannomas.
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  • 文章类型: Case Reports
    背景:黄色瘤是一种肉芽肿性病变,由循环血清脂蛋白泄漏到周围组织而形成。孤立的颅内黄色瘤很少报道,通常被误诊。在高脂血症患者中也很少发现颅内黄色瘤。据作者所知,以前没有研究和文献报道双侧额叶颅内黄色瘤受累。
    方法:作者报道了一例罕见的病例,在一名42岁的女性中,双侧额叶颅内黄色瘤受累并伴有II型高脂血症。宏观上,肿瘤呈灰黄色,呈脆性,固体的一致性。组织病理学检查显示,许多充满脂质的巨噬细胞被囊性,坏死,部分出血区,部分由血铁皮噬菌体和增生性毛细血管组成。组织病理学表现为黄色瘤的特征。
    结论:双侧额叶颅内黄色瘤合并II型高脂血症是一个不寻常的发现。尽管其罕见且放射学表现多种多样,应将其视为颅内和轴内病变的鉴别诊断之一。需要进行组织病理学检查以排除其他鉴别诊断。
    BACKGROUND: Xanthoma is a granulomatous lesion that develops from leakage of circulating serum lipoprotein into the surrounding tissue. An isolated intracranial xanthoma is rarely reported and usually misdiagnosed. Intracranial xanthoma is also rarely found in patients with hyperlipidemia. To the best of the authors\' knowledge, no previous studies and literature have reported bilateral involvement of intracranial xanthoma in the frontal lobe.
    METHODS: The authors reported an unusual case of bilateral involvement of intracranial xanthoma in the frontal lobe with associated type II hyperlipidemia in a 42-year-old woman. Macroscopically, the tumor had an appearance of greyish-yellow color with a brittle, solid consistency. Histopathological examination revealed numerous lipid-laden macrophages surrounded by a cystic, necrotic, partially hemorrhagic area, with some parts consisting of hemosiderophages and proliferative capillary blood vessels. The histopathological findings indicated the characteristics of xanthoma.
    CONCLUSIONS: Bilateral frontal intracranial xanthoma with associated type II hyperlipidemia is an unusual finding. Despite its rarity and wide variety of radiological presentations, it should be considered one of the differential diagnoses of lesions that develop intracranially and intraaxially. Confirmation with histopathological examination is needed to exclude from other differential diagnoses.
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