Abstract：
The qualitative fit testing procedure would be challenging due to severe shortages, high cost, and unavailability of commercial fit test kits in the marketplaces during pandemics of respiratory infectious diseases. Assessment of alternatives for commercial fit test kits to be prepared for emergencies is critically required. This study aimed to investigate the feasibility of an alternative of the Accumed NF60 nebulizer for the Occupational Safety and Health Administration (OSHA)-approved Allegro nebulizer.
Thirty-two participants were randomly allocated to 6 filtering facepiece respirators (FFRs). They were qualitatively fit tested by both manual Allegro and automated Accumed NF60 nebulizers.
There was no statistically significant difference between the Allegro and Accumed NF60 nebulizers by passing rates. The odds for passing fit testing using the Accumed NF60 nebulizer was similar to that of the Allegro one (odds ratio=1.0, 95% confidence interval [0.58-1.74]).
The Accumed NF60 nebulizer could be used as a cost-benefit substitute for the standard fit test nebulizers in the pandemic situation where there is a shortage and difficulty of access. It is more convenient, decreases the time investment, and reduces the contact stress in the operators\' hands as it does not require squeezing the nebulizer bulb frequently. The test solutions\' preparation and fit testing procedures on many personnel are more straightforward, efficient, and hygienic than the Allegro one.
Thirty-two participants were randomly allocated to 6 filtering facepiece respirators (FFRs). They were qualitatively fit tested by both manual Allegro and automated Accumed NF60 nebulizers.
There was no statistically significant difference between the Allegro and Accumed NF60 nebulizers by passing rates. The odds for passing fit testing using the Accumed NF60 nebulizer was similar to that of the Allegro one (odds ratio=1.0, 95% confidence interval [0.58-1.74]).
The Accumed NF60 nebulizer could be used as a cost-benefit substitute for the standard fit test nebulizers in the pandemic situation where there is a shortage and difficulty of access. It is more convenient, decreases the time investment, and reduces the contact stress in the operators\' hands as it does not require squeezing the nebulizer bulb frequently. The test solutions\' preparation and fit testing procedures on many personnel are more straightforward, efficient, and hygienic than the Allegro one.
摘要：
目标：由于严重短缺，定性拟合测试程序将具有挑战性，高成本,以及在呼吸道传染病大流行期间，市场上无法获得商业拟合测试试剂盒。迫切需要评估为紧急情况准备的商业适合测试套件的替代品。本研究旨在研究职业安全与健康管理局（OSHA）批准的Allegro雾化器替代NF60雾化器的可行性。
方法：将32名参与者随机分配到6台过滤面罩呼吸器（FFR）中。通过手动Allegro和自动累积NF60雾化器对它们进行了定性测试。
结果：Allegro和AccumpedNF60雾化器之间的通过率没有统计学上的显着差异。使用累积NF60雾化器通过拟合测试的几率与Allegro雾化器相似(优势比=1.0,95%置信区间[0.58-1.74])。
结论：累积的NF60雾化器可以在缺乏和难以接近的大流行情况下用作标准配合测试雾化器的成本效益替代品。它更方便，减少时间投资，并减少了操作人员手中的接触应力，因为它不需要经常挤压雾化器灯泡。测试解决方案的准备和适合许多人员的测试程序更简单，高效,比快板更卫生.
方法：将32名参与者随机分配到6台过滤面罩呼吸器（FFR）中。通过手动Allegro和自动累积NF60雾化器对它们进行了定性测试。
结果：Allegro和AccumpedNF60雾化器之间的通过率没有统计学上的显着差异。使用累积NF60雾化器通过拟合测试的几率与Allegro雾化器相似(优势比=1.0,95%置信区间[0.58-1.74])。
结论：累积的NF60雾化器可以在缺乏和难以接近的大流行情况下用作标准配合测试雾化器的成本效益替代品。它更方便，减少时间投资，并减少了操作人员手中的接触应力，因为它不需要经常挤压雾化器灯泡。测试解决方案的准备和适合许多人员的测试程序更简单，高效,比快板更卫生.
