Abstract：
Various medications, surgeries, and assisted reproductive techniques are used to treat male infertility, but the high cost and low effectiveness have made these methods unpopular. The use of herbal medicines such as Withania somnifera, Ceratonia siliqua, Nigella sativa and Alpinia officinarum for the treatment of male infertility has become highly popular in recent years.
We conducted this systematic review to evaluate the recent scientific evidence regarding herbal medicines used to treat idiopathic male infertility (IMI).
Online literature resources were checked using different search engines, including ISI, Web of Knowledge, Medline, PubMed, Scopus, and Google Scholar. Date restrictions were applied to 2020, and the publication language was restricted to English and Persian. The risk of bias was evaluated using the Cochrane method.
Out of 851 articles, 14 trials with 1218 participants were included. Of the 15 plants and medicinal products introduced in the selected studies, 12 cases were effective in treating male infertility. Each of these plants or products affects specific components of male fertility for which various mechanisms were mentioned, but most of them had antioxidant effects. No serious side effects were reported.
Whitania somnifera roots, Alpinia officinarum, Nigella sativa seeds, Tomato, and Ceratonia siliqua and the formulation of Xperm, PHF, Churna Ratnam, Svaguptadi Churna, Y virilin capsule, manix capsule, and Tradafertil tablet revealed successful outcomes in treatment of idiopathic male infertility.
We conducted this systematic review to evaluate the recent scientific evidence regarding herbal medicines used to treat idiopathic male infertility (IMI).
Online literature resources were checked using different search engines, including ISI, Web of Knowledge, Medline, PubMed, Scopus, and Google Scholar. Date restrictions were applied to 2020, and the publication language was restricted to English and Persian. The risk of bias was evaluated using the Cochrane method.
Out of 851 articles, 14 trials with 1218 participants were included. Of the 15 plants and medicinal products introduced in the selected studies, 12 cases were effective in treating male infertility. Each of these plants or products affects specific components of male fertility for which various mechanisms were mentioned, but most of them had antioxidant effects. No serious side effects were reported.
Whitania somnifera roots, Alpinia officinarum, Nigella sativa seeds, Tomato, and Ceratonia siliqua and the formulation of Xperm, PHF, Churna Ratnam, Svaguptadi Churna, Y virilin capsule, manix capsule, and Tradafertil tablet revealed successful outcomes in treatment of idiopathic male infertility.
摘要：
各种药物,手术,辅助生殖技术用于治疗男性不育，但是高成本和低有效性使这些方法不受欢迎。使用草药，如Withaniasomnifera，西利夸角角,近年来，用于治疗男性不育症的黑麦草和高良姜已变得非常流行。
我们进行了这项系统评价，以评估有关用于治疗特发性男性不育症（IMI）的草药的最新科学证据。
使用不同的搜索引擎检查了在线文献资源，包括ISI,WebofKnowledge,Medline,PubMed,Scopus,谷歌学者。日期限制适用于2020年，出版语言仅限于英语和波斯语。使用Cochrane方法评估偏倚风险。
在851篇文章中，纳入了14项试验，1218名参与者。在选定的研究中引入的15种植物和药用产品中，治疗男性不育12例。这些植物或产品中的每一种都会影响男性生育力的特定组成部分，其中提到了各种机制。但大多数都有抗氧化作用。没有报告严重的副作用。
Whitaniasomnifera根，高良姜,黑麦草种子，番茄,和Ceratoniasiliqua和Xperm的配方，PHF,ChurnaRatnam,SvaguptadiChurna,Y维林胶囊，马尼胶囊,和Tradafertil片显示了特发性男性不育症的成功治疗结果。
我们进行了这项系统评价，以评估有关用于治疗特发性男性不育症（IMI）的草药的最新科学证据。
使用不同的搜索引擎检查了在线文献资源，包括ISI,WebofKnowledge,Medline,PubMed,Scopus,谷歌学者。日期限制适用于2020年，出版语言仅限于英语和波斯语。使用Cochrane方法评估偏倚风险。
在851篇文章中，纳入了14项试验，1218名参与者。在选定的研究中引入的15种植物和药用产品中，治疗男性不育12例。这些植物或产品中的每一种都会影响男性生育力的特定组成部分，其中提到了各种机制。但大多数都有抗氧化作用。没有报告严重的副作用。
Whitaniasomnifera根，高良姜,黑麦草种子，番茄,和Ceratoniasiliqua和Xperm的配方，PHF,ChurnaRatnam,SvaguptadiChurna,Y维林胶囊，马尼胶囊,和Tradafertil片显示了特发性男性不育症的成功治疗结果。
