Abstract：
To estimate the prevalence of neuropsychiatric disorders, including autism spectrum disorders (ASDs), attention-deficit hyperactivity disorder (ADHD), depression, anxiety disorders, and obsessive-compulsive disorder (OCD), in populations with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD).
MEDLINE (via PubMed), Scopus, Web of Science, and Cochrane Library from inception to November 2021.
Observational studies of individuals with DMD or BMD that estimated the prevalence of ASDs, ADHD, depression, anxiety disorders, and OCD in each population.
A random-effects meta-analysis was performed on each outcome and each population (ie, DMD, BMD).
Twenty-three studies were included in the meta-analysis. In DMD, there was a prevalence of 7.0% of ASDs, 18.0% of ADHD, 11.0% of depression, 24.0% of anxiety disorders, and 12.0% of OCD. Furthermore, in BMD, there was a prevalence of 6.0% of ASDs, 28.0% of ADHD, 7.0% of depression, 25.0% of anxiety disorders, and 7.0% of OCD.
The prevalence of these neuropsychiatric disorders is higher among patients with DMD or BMD than among the general population, and the presence of these disorders may negatively influence optimal medical management.
MEDLINE (via PubMed), Scopus, Web of Science, and Cochrane Library from inception to November 2021.
Observational studies of individuals with DMD or BMD that estimated the prevalence of ASDs, ADHD, depression, anxiety disorders, and OCD in each population.
A random-effects meta-analysis was performed on each outcome and each population (ie, DMD, BMD).
Twenty-three studies were included in the meta-analysis. In DMD, there was a prevalence of 7.0% of ASDs, 18.0% of ADHD, 11.0% of depression, 24.0% of anxiety disorders, and 12.0% of OCD. Furthermore, in BMD, there was a prevalence of 6.0% of ASDs, 28.0% of ADHD, 7.0% of depression, 25.0% of anxiety disorders, and 7.0% of OCD.
The prevalence of these neuropsychiatric disorders is higher among patients with DMD or BMD than among the general population, and the presence of these disorders may negatively influence optimal medical management.
摘要：
为了估计神经精神疾病的患病率，包括自闭症谱系障碍（ASDs），注意缺陷多动障碍（ADHD），抑郁症,焦虑症,强迫症（OCD），在杜兴氏肌营养不良(DMD)和贝克尔肌营养不良(BMD)人群中。
MEDLINE（通过PubMed），Scopus,WebofScience,和Cochrane图书馆从成立到2021年11月。
对DMD或BMD患者的观察性研究估计了ASD的患病率，多动症,抑郁症,焦虑症,每个人群的强迫症。
对每个结果和每个人群进行了随机效应荟萃分析（即，DMD,BMD）。
23项研究纳入荟萃分析。在DMD中,ASD的患病率为7.0%，ADHD的18.0%，抑郁症的11.0%，24.0%的焦虑症，和强迫症的12.0%。此外，在BMD中，ASD的患病率为6.0%，28.0%的ADHD,抑郁症的7.0%，25.0％的焦虑症，和强迫症的7.0%。
患有DMD或BMD的患者中这些神经精神疾病的患病率高于普通人群。这些疾病的存在可能会对最佳医疗管理产生负面影响。
MEDLINE（通过PubMed），Scopus,WebofScience,和Cochrane图书馆从成立到2021年11月。
对DMD或BMD患者的观察性研究估计了ASD的患病率，多动症,抑郁症,焦虑症,每个人群的强迫症。
对每个结果和每个人群进行了随机效应荟萃分析（即，DMD,BMD）。
23项研究纳入荟萃分析。在DMD中,ASD的患病率为7.0%，ADHD的18.0%，抑郁症的11.0%，24.0%的焦虑症，和强迫症的12.0%。此外，在BMD中，ASD的患病率为6.0%，28.0%的ADHD,抑郁症的7.0%，25.0％的焦虑症，和强迫症的7.0%。
患有DMD或BMD的患者中这些神经精神疾病的患病率高于普通人群。这些疾病的存在可能会对最佳医疗管理产生负面影响。
