Abstract：
OBJECTIVE: To compare the results and 5- and 8-year overall survival (OS) and disease-free survival (DFS) of hand-assisted laparoscopic surgery (HALS) and laparoscopic-assisted surgery (LAS) in radical gastrectomy for advanced distal gastric cancer.
METHODS: A total of 124 patients admitted to our institution from May 2009 to April 2013 were randomly divided into a HALS group (n = 62) and a LAS group (n = 62). Postoperatively, 110 patients were followed for 5 and 8 years, and 14 patients were lost to follow-up. The 5- and 8-year OS and DFS rates of the groups were compared and analyzed.
RESULTS: The 5- and 8-year OS rates, respectively, were 38.8% and 19.4% in the HALS group and 38.3% and 15.3% in the LAS group (log-rank test, χ2 = 0.250). The 5- and 8-year DFS rates, respectively, were 23.1% and 10.6% in the HALS group and 19.3% and 11.6% in the LAS group (log-rank test, χ2 = 0.109). No significant differences were found.
CONCLUSIONS: Compared with LAS, HALS radical gastrectomy for advanced distal gastric cancer had a lower conversion rate to open surgery, shorter surgical duration, and more thorough dissection of lymph nodes; 5- and 8-year OS and DFS rates were similar to those with LAS.
METHODS: A total of 124 patients admitted to our institution from May 2009 to April 2013 were randomly divided into a HALS group (n = 62) and a LAS group (n = 62). Postoperatively, 110 patients were followed for 5 and 8 years, and 14 patients were lost to follow-up. The 5- and 8-year OS and DFS rates of the groups were compared and analyzed.
RESULTS: The 5- and 8-year OS rates, respectively, were 38.8% and 19.4% in the HALS group and 38.3% and 15.3% in the LAS group (log-rank test, χ2 = 0.250). The 5- and 8-year DFS rates, respectively, were 23.1% and 10.6% in the HALS group and 19.3% and 11.6% in the LAS group (log-rank test, χ2 = 0.109). No significant differences were found.
CONCLUSIONS: Compared with LAS, HALS radical gastrectomy for advanced distal gastric cancer had a lower conversion rate to open surgery, shorter surgical duration, and more thorough dissection of lymph nodes; 5- and 8-year OS and DFS rates were similar to those with LAS.
摘要：
目的：比较手助腹腔镜手术（HALS）和腹腔镜辅助手术（LAS）在进展期远端胃癌根治术中的结果以及5年和8年总生存期（OS）和无病生存期（DFS）。
方法：将我院2009年5月至2013年4月收治的124例患者随机分为HALS组（n=62）和LAS组（n=62）。术后,110例患者随访5年和8年，14例患者失访。比较各组5年和8年OS和DFS率。
结果：5年和8年OS率，分别,HALS组中分别为38.8%和19.4%，LAS组中分别为38.3%和15.3%(对数秩检验，χ2=0.250)。5年和8年DFS率，分别,在HALS组中分别为23.1％和10.6％，在LAS组中分别为19.3％和11.6％（对数秩检验，χ2=0.109)。没有发现显著差异。
结论：与LAS相比，HALS胃癌根治术对进展期远端胃癌的开腹手术转化率较低，手术时间较短，淋巴结清扫更彻底；5年和8年OS和DFS率与LAS相似。
方法：将我院2009年5月至2013年4月收治的124例患者随机分为HALS组（n=62）和LAS组（n=62）。术后,110例患者随访5年和8年，14例患者失访。比较各组5年和8年OS和DFS率。
结果：5年和8年OS率，分别,HALS组中分别为38.8%和19.4%，LAS组中分别为38.3%和15.3%(对数秩检验，χ2=0.250)。5年和8年DFS率，分别,在HALS组中分别为23.1％和10.6％，在LAS组中分别为19.3％和11.6％（对数秩检验，χ2=0.109)。没有发现显著差异。
结论：与LAS相比，HALS胃癌根治术对进展期远端胃癌的开腹手术转化率较低，手术时间较短，淋巴结清扫更彻底；5年和8年OS和DFS率与LAS相似。
