%0 Journal Article
%T Hand-assisted laparoscopic versus laparoscopic-assisted radical gastrectomy in the treatment of advanced distal gastric cancer: final results of a single-center randomized study.
%A Luo G
%A Xiang Q
%A Wang X
%A Li Y
%A Cao Y
%A Gong J
%A Li Y
%A Luo G
%A Xiang Q
%A Wang X
%A Li Y
%A Cao Y
%A Gong J
%A Li Y
%J J Int Med Res
%V 50
%N 7
%D Jul 2022
%M 35822251
%F 1.573
%R 10.1177/03000605221109361
%X <B>OBJECTIVE: </B>To compare the results and 5- and 8-year overall survival (OS) and disease-free survival (DFS) of hand-assisted laparoscopic surgery (HALS) and laparoscopic-assisted surgery (LAS) in radical gastrectomy for advanced distal gastric cancer.<BR><B>METHODS: </B>A total of 124 patients admitted to our institution from May 2009 to April 2013 were randomly divided into a HALS group (n = 62) and a LAS group (n = 62). Postoperatively, 110 patients were followed for 5 and 8 years, and 14 patients were lost to follow-up. The 5- and 8-year OS and DFS rates of the groups were compared and analyzed.<BR><B>RESULTS: </B>The 5- and 8-year OS rates, respectively, were 38.8% and 19.4% in the HALS group and 38.3% and 15.3% in the LAS group (log-rank test, χ2 = 0.250). The 5- and 8-year DFS rates, respectively, were 23.1% and 10.6% in the HALS group and 19.3% and 11.6% in the LAS group (log-rank test, χ2 = 0.109). No significant differences were found.<BR><B>CONCLUSIONS: </B>Compared with LAS, HALS radical gastrectomy for advanced distal gastric cancer had a lower conversion rate to open surgery, shorter surgical duration, and more thorough dissection of lymph nodes; 5- and 8-year OS and DFS rates were similar to those with LAS.