Thoracic spine

胸椎
  • 文章类型: Journal Article
    肩袖相关肩痛(RCRSP)是一种普遍的临床表现,其特征是诊断不确定性很大。这种不确定性中的一些与颈椎和胸椎的参与是RCRSP的来源或促成因素有关。32例RCRSP病例和32例无症状对照(AC),2023年3月至2023年9月从拉巴斯-卡洛斯三世医院招募,年龄相匹配,性别和手部优势。评估变量包括宫颈,胸部活动范围(ROM)和颈部残疾指数(NDI)。使用独立的t检验来比较这些测量值中的每一个,并使用多元线性回归来检查颈部或心理社会变量预测NDI变异性的能力。RCRSP组颈椎旋转明显减少[RCRSP(111.14±22.98);AC(130.23±21.20),d=0.86,p<0.01]和柔性扩展ROM[RCRSP(112.47±2.07);AC(128.5±17.85),d=0.80,p<0.01]以及胸椎屈曲[RCRSP(33.02±1.14);AC(34.14±1.01),d=1.04,p<0.01],扩展[RCRSP(28.63±0.89);AC(27.37±0.89),d=-1.40,p<0.01],右旋转[RCRSP(40.53±10.39);AC(54.45±9.75),d=1.38,p<0.01],向左旋转[RCRSP(39.00±11.26);AC(54.10±10.51),d=1.39,p<0.01],NDI评分[RCRSP(17.56±7.25);AC(2.47±3.25),d=-2.69,p<0.01]。最能解释颈部残疾的变量是中枢致敏指数和SF-12总分(调整后的R2=0.75;p<0.01)。这些结果表明,临床医生应评估RCRSP患者的颈椎和胸椎活动度。
    Rotator cuff related shoulder pain (RCRSP) is a prevalent clinical presentation characterized by substantial diagnostic uncertainty. Some of this uncertainty relates to the involvement of the cervical and thoracic spine as a source of or contributing factor to RCRSP. Thirty-two RCRSP cases and thirty-two asymptomatic controls (AC), recruited from Hospital La Paz-Carlos III between March 2023 and September 2023, were matched for age, gender and hand dominance. Assessed variables included cervical, thoracic range of motion (ROM) and neck disability index (NDI). Independent t-tests were used to compare each of these measurements and multiple linear regression was used to examine the capacity of neck or psychosocial variables to predict the variability of the NDI. The RCRSP group had significantly reduced cervical rotation [RCRSP (111.14 ± 22.98); AC (130.23 ± 21.20), d = 0.86, p < 0.01] and flexo-extension ROM [RCRSP (112.47 ± 2.07); AC (128.5 ± 17.85), d = 0.80, p < 0.01] as well as thoracic spine flexion [RCRSP (33.02 ± 1.14); AC (34.14 ± 1.01), d = 1.04, p < 0.01], extension [RCRSP (28.63 ± 0.89); AC (27.37 ± 0.89), d = -1.40, p < 0.01], right rotation [RCRSP (40.53 ± 10.39); AC (54.45 ± 9.75), d = 1.38, p < 0.01], left rotation [RCRSP (39.00 ± 11.26); AC (54.10 ± 10.51), d = 1.39, p < 0.01] and a significantly increased NDI score [RCRSP (17.56 ± 7.25); AC (2.47 ± 3.25), d = -2.69, p < 0.01]. The variables best explaining neck disability were central sensitization index and SF-12 total score (adjusted R2 = 0.75; p < 0.01). These results suggest that clinicians should assess cervical and thoracic spine mobility in patients with RCRSP.
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  • 文章类型: English Abstract
    Morphology of injuries following gunshot wounds requires specific treatment approaches. Currently, there are no similar classifications for assessing fracture stability with subsequent tactical recommendations. Taking into account diagnostic limitations (contraindications for MRI due to implantable metal fragments, limitations of functional radiography of the spine in seriously injured patients), we make decisions considering CT data. In this study, we will determine severity of vertebral damage and effect of these damages on mechanical stability of spinal motion segments. In the future, CT-based assessment of inter-expert agreement will be performed. Finally, we will propose the scoring system for classification of spinal gunshot wounds.
    OBJECTIVE: To present a research protocol for development of new scoring system for unstable spinal gunshot wounds based on inter-expert agreement assessment.
    METHODS: To create a new tactical classification, we will distinguish and analyze clinical and CT data of patients with thoracolumbar spinal gunshot wounds. The Delphi method will be used to collaborate between several surgeons. A three-stage study will result a questionnaire (for 30 clinical cases). We will develop tactical scoring system and analyze statistical data (kappa).
    CONCLUSIONS: Various classifications have been developed for closed spinal injuries. These systems describe the nature of injury and allow one to develop tactical decisions for further actions. Another mechanism of injuries following gunshot wounds does not allow the classification of closed injuries to be adequately applied in some cases. Indeed, spinal structures follow either direct passage of a wounding projectile through the spine or transferring the energy of this projectile in contrast to classical compression, distraction and rotational-translation mechanisms typical for closed trauma.
    Морфология повреждений при огнестрельных ранениях требует специфических подходов к тактике лечения данной группы пациентов. В настоящее время отсутствуют подобные классификации для оценки стабильности перелома с последующими тактическими рекомендациями. Учитывая диагностические ограничения (противопоказания к магнитно-резонансной томографии из-за наличия металлических осколков в теле, ограничение применения функциональной рентгенографии позвоночника у тяжелораненых), все решения принимаются на основе анализа компьютерной томограммы. В исследовании планируется определить тяжесть повреждений анатомических структур позвонков, влияние этих повреждений на механическую стабильность позвоночно-двигательного сегмента. В дальнейшем на основе анализа данных компьютерной томограммы будет проанализирован уровень согласия хирургов-экспертов и предложена балльная оценка стабильности по новой классификации огнестрельных ранений позвоночника.
    UNASSIGNED: Представить протокол исследования по разработке новой тактической классификации, позволяющей произвести балльную оценку стабильности повреждения в позвоночно-двигательном сегменте при огнестрельных ранениях на базе оценки уровня согласия в группе хирургов-экспертов.
    UNASSIGNED: Для создания новой тактической классификации планируется выделить и проанализировать результаты клинических данных и компьютерно-томографические исследования пациентов с огнестрельным ранением грудопоясничного отдела позвоночника, соответствующих критериям включения. Для совместной работы нескольких хирургов будет применен метод Delphi. В результате трехэтапного исследования будет составлен опросник (для 30 клинических случаев), разработана балльная тактико-хирургическая классификация и проведен статистический анализ полученных данных (kappa).
    UNASSIGNED: Для закрытых повреждений позвоночника разработаны классификации, которые описывают характер травмы и позволяют выработать тактические решения для дальнейших действий. Иной механизм повреждения при огнестрельных ранениях в ряде случаев не позволяет адекватно применить классификации закрытых повреждений, так как переломы структур позвоночника возникают в результате или прямого прохождения через них ранящего снаряда, или путем передачи энергии от снаряда, а не в результате классических компрессионных, дистракционных и ротационно-трансляционных механизмов при закрытой травме.
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  • 文章类型: Case Reports
    此病例报告描述了一种罕见的表现为蛛网膜下腔出血的胸椎霉菌性脊髓前动脉瘤。孤立的脊髓前动脉瘤极为罕见。虽然这种情况可能发生在可能导致休克的潜在感染的背景下,感染本身的其他体征和症状通常在动脉瘤发展和随后的出血之前出现。我们介绍了一例30岁的男性,他患有急性起病的双侧下肢运动性截瘫,并被发现患有与孤立的胸椎前动脉瘤有关的弥漫性蛛网膜下腔出血。这被认为是真菌的起源。脊柱血管造影显示T11-T12级别的动脉瘤起源于脊髓前动脉,导致脊髓弥漫性蛛网膜下腔出血。密切随访患者,并表现出运动功能的进行性改善。两周后进行磁共振成像显示鞘内出血减少,轻度脊髓水肿,以及脊髓前动脉瘤的离散可视化减少。我们介绍了一个独特的病例,即胸椎中孤立的脊髓前动脉瘤,并伴有蛛网膜下腔出血。这种情况是独特的,因为临床表现和影像学检查结果强烈提示动脉瘤的真菌病因。尽管没有明确的组织病理学证实。据我们所知,这是首例报道的疑似真菌来源的孤立性胸腔ASA动脉瘤病例.
    This case report describes a rare presentation of a mycotic anterior spinal artery aneurysm of the thoracic spine presenting as a subarachnoid hemorrhage. Isolated anterior spinal artery aneurysms are exceedingly rare. While this condition can occur in the setting of an underlying infection that may lead to shock, other signs and symptoms of the infection itself typically manifest before the development of the aneurysm and subsequent hemorrhage. We present a case of a 30-year-old male who presented with acute-onset bilateral lower extremity motor paraplegia and was found to have diffuse subarachnoid hemorrhage related to an isolated thoracic anterior spinal artery aneurysm, which was believed to be mycotic in origin. Spinal angiogram revealed evidence of an aneurysm originating from the anterior spinal artery at the T11-T12 level, contributing to diffuse subarachnoid hemorrhage of the spinal cord. The patient was followed closely and exhibited progressive improvement in motor function. Magnetic resonance imaging performed two weeks later revealed decreased intrathecal hemorrhage, mild spinal cord edema, and a reduction in the discrete visualization of the anterior spinal artery aneurysm. We present a unique case of an isolated anterior spinal artery aneurysm in the thoracic spine presenting with subarachnoid hemorrhage. This case is distinctive in that the clinical presentation and radiographic findings strongly suggest a mycotic etiology for the aneurysm, despite the absence of definitive histopathologic confirmation. To our knowledge, this is the first reported case of an isolated thoracic ASA aneurysm suspected to be mycotic in origin.
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  • 文章类型: Journal Article
    骨质疏松症的诊断不足,而通过使用定量计算机断层扫描(QCT)测量骨矿物质密度(BMD)可检测到。先前已建议使用腰椎QCT进行低BMD的机会性筛查。然而,胸椎QCT也具有这种潜力,以发展上和下截断值为低胸椎,对应于腰椎BMD的当前截止值。在提到胸痛的参与者中,腰椎和胸部BMD使用非对比腰椎和心脏CT扫描进行测量。腰椎BMD截止值非常低(<80mg/cm3),低(80-120mg/cm3),和正常BMD(>120mg/cm3)用于评估相应的胸廓值。线性回归可以识别新的诊断胸部BMD截止值。177名参与者(平均年龄61岁[范围31-74岁],51%的女性)腰椎BMD为121.6mg/cm3(95%CI115.9-127.3),胸椎BMD为137.0mg/cm3(95%CI:131.5-142.5),p<0.001。腰椎骨密度分类显示14%,35%,每个BMD类别为45%。当应用于胸部BMD测量时,25%的参与者被重新分类为较低的组。线性回归预测胸椎BMD=0.85*腰椎BMD+33.5的关系,产生<102和>136mg/cm3的调整胸椎截断值。发现腰椎和胸部区域之间的BMD存在显着差异,但是线性关系使胸椎低BMD的胸椎上下截断值得以发展。由于胸部CT扫描很频繁,这些发现将加强CT图像对骨质疏松症的机会性检测的利用。
    Osteoporosis is under-diagnosed while detectable by measuring bone mineral density (BMD) using quantitative computer tomography (QCT). Opportunistic screening for low BMD has previously been suggested using lumbar QCT. However, thoracic QCT also possesses this potential to develop upper and lower cut-off values for low thoracic BMD, corresponding to the current cut-offs for lumbar BMD. In participants referred with chest pain, lumbar and thoracic BMD were measured using non-contrast lumbar- and cardiac CT scans. Lumbar BMD cut-off values for very low (< 80 mg/cm3), low (80-120 mg/cm3), and normal BMD (> 120 mg/cm3) were used to assess the corresponding thoracic values. A linear regression enabled identification of new diagnostic thoracic BMD cut-off values. The 177 participants (mean age 61 [range 31-74] years, 51% women) had a lumbar BMD of 121.6 mg/cm3 (95% CI 115.9-127.3) and a thoracic BMD of 137.0 mg/cm3 (95% CI: 131.5-142.5), p < 0.001. Categorization of lumbar BMD revealed 14%, 35%, and 45% in each BMD category. When applied for the thoracic BMD measurements, 25% of participants were reclassified into a lower group. Linear regression predicted a relationship of Thoracic BMD = 0.85 * Lumbar BMD + 33.5, yielding adjusted thoracic cut-off values of < 102 and > 136 mg/cm3. Significant differences in BMD between lumbar and thoracic regions were found, but a linear relationship enabled the development of thoracic upper and lower cut-off values for low BMD in the thoracic spine. As Thoracic CT scans are frequent, these findings will strengthen the utilization of CT images for opportunistic detection of osteoporosis.
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  • 文章类型: Case Reports
    脊索瘤是生长缓慢的,局部侵入性,属于肉瘤家族的低度肿瘤。它主要影响骶骨和颅底。我们介绍了一例胸部脊索瘤,最初表现为硬膜外血肿(EDH),这是一个罕见的临床实体。我们报道了这个病例,并进行了PRISMA驱动的系统评价,以总结文献中的类似病例.本文就胸椎脊索瘤的临床特点及转归作一综述。我们的案子涉及一个60岁的男性,尽管没有外伤史,表现为急性轻瘫。在T6水平发现硬膜外血肿,导致涉及T4-6椎板切除术和固定的手术干预。手术后六个月,患者出现进行性下肢无力和痉挛。计算机断层扫描(CT)显示T6侵蚀和相关的侵袭性肿块。磁共振成像(MRI)显示,D6的椎体和右侧椎弓根产生了一个巨大的异质软组织肿块,突出在硬膜外腔中,并在该水平处局部压迫脊髓。测量的质量约为5×4×3.5cm。磁共振脊髓造影显示T5-6水平的充盈缺损,确认软组织病变的椎管内位置。完全切除肿块证实了胸椎脊索瘤的诊断。术后随访显示下肢痉挛和轻瘫明显改善,患者开始辅助放疗。此案强调了在评估类似EDH的演示文稿时保持高怀疑指数的重要性。
    A chordoma is a slow growing, locally invasive, low-grade tumor belonging to the sarcoma family. It mainly affects the sacrum and skull base. We present a case of thoracic chordoma initially presented with epidural hematoma (EDH), which is a rare clinical entity. We reported this case, and also performed a PRISMA-driven systematic review to summary the similar cases in the literature. This review includes the clinical characteristics and outcome of thoracic chordoma. Our case involves a 60-year-old male who, despite no history of trauma, presented with acute paraparesis. An epidural hematoma was identified at T6 level, leading to a surgical intervention involving T4-6 laminectomy and fixation. Six months subsequent to surgery, the patient experienced progressive lower limb weakness and spasticity. Computed tomography (CT) exhibited erosion of T6 and an associated aggressive mass. Magnetic resonance imaging (MRI) revealed a large heterogenous soft tissue mass arising from the vertebral body and right pedicle of D6, protruding in the epidural space and compressing the spinal cord focally at this level. The mass measured approximately 5 × 4 × 3.5 cm. Magnetic resonance myelography indicated a filling defect at T5-6 level, confirming the intraspinal location of the soft tissue lesion. Complete excision of the mass confirmed the diagnosis of thoracic chordoma. Postoperative follow-up demonstrated notable improvement in the lower limb spasticity and paraparesis, and the patient started adjuvant radiotherapy. This case underscores the importance of maintaining a high index of suspicion when evaluating presentations resembling EDH.
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  • 文章类型: Case Reports
    新生隐球菌是一种真菌感染,主要影响免疫功能低下个体的中枢神经系统和肺。已知脊柱感染是隐球菌病的罕见表现。在这里,我们报告一例患者在T10椎骨上有孤立的非特异性脊柱病变.患者接受了抗真菌药物的非手术治疗,导致满意的临床结果。
    Cryptococcus neoformans is a type of fungal infection, which primarily affects the central nervous system and lungs of immunocompromised individuals. Spinal infections are known to be a rare manifestation of cryptococcosis. Herein, we report a case of a patient with isolated nonspecific spinal lesions at the T10 vertebra. The patient received non-surgical treatment with antifungal drugs, resulting in satisfactory clinical outcomes.
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  • 文章类型: Journal Article
    背景:使用三维图像分析,我们以前报道过颈椎后纵韧带骨化(OPLL)后路融合手术后骨化进展受到抑制.这里,我们旨在使用三维分析评估胸部OPLL的形态变化.
    方法:17例患者(男8例,女9例;平均年龄,56.9年)的患者接受了胸OPLL的后路减压和融合(PDF)。我们使用一种新颖的分析来评估OPLL体积,该分析涉及从计算机断层扫描图像创建三维模型以精确测量体积。此外,OPLL厚度,宽度,在矢状和轴向计算机断层扫描平面上测量长度。我们研究了PDF后OPLL的形态变化。此外,将患者分为体积减少组和体积增加组,并比较相关因素.
    结果:术前平均OPLL体积为1,677mm3,最终检查为1,705mm3,没有显着差异。在17例中的7例中观察到体积减少(41%)。尽管OPLL宽度和长度在术后显著增加,OPLL厚度从术前7.1mm明显减少到术后6.5mm(所有,p<0.05)。与体积增加组(-0.06mm/年)相比,体积减少组(-0.36mm/年)的年厚度变化显着差异(p<0.05)。
    结论:PDF后胸部OPLL在前后方向变薄,但在水平方向和颅尾方向增加。OPLL厚度的减少与骨化体积的减少有关。我们认为胸部OPLL的体积减少受硬膜囊脉动的影响。
    BACKGROUND: Using three-dimensional image analysis, we previously reported suppression of ossification progression following posterior fusion surgery for cervical ossification of the posterior longitudinal ligament (OPLL). Here, we aimed to evaluate the morphological changes in thoracic OPLL using three-dimensional analysis.
    METHODS: Seventeen patients (eight males and nine females; mean age, 56.9 years) who underwent posterior decompression and fusion (PDF) for thoracic OPLL were included. We evaluated the OPLL volume using a novel analysis involving creating a three-dimensional model from computed tomography images to measure the volume accurately. Additionally, OPLL thickness, width, and length were measured on sagittal and axial computed tomography planes. We investigated the morphological changes in OPLL after PDF. Furthermore, patients were classified into reduced volume and increased volume groups and associated factors were compared.
    RESULTS: The mean OPLL volume was 1,677 mm3 preoperatively and 1,705 mm3 at the final examination and did not significantly differ. Volume reduction was observed in 7 of 17 cases (41 %). Although OPLL width and length significantly increased postoperatively, OPLL thickness significantly reduced from 7.1 mm preoperatively to 6.5 mm postoperatively (all, p < 0.05). The annual thickness changes significantly differed (p <0.05) in the reduced volume group (-0.36 mm/year) compared to that in the increased volume group (-0.06 mm/year).
    CONCLUSIONS: Thoracic OPLL after PDF becomes thinner in the anteroposterior direction but increases horizontally and craniocaudally. The reduction in OPLL thickness was related to a reduction in ossification volume. We believe that volume reduction in thoracic OPLL is influenced by pulsation of the dural sac.
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  • 文章类型: Journal Article
    急性创伤性脊髓损伤(tSCI)是一种复杂的异质性损伤,受伤的程度,损伤严重程度,脊髓压迫的持续时间和程度,血压管理似乎影响神经系统的结果。尽管文献中的数据似乎在胸椎和胸腰椎tSCI患者的手术减压和脊柱固定的有效性方面不一致,但一些单中心研究表明,早期手术减压可能会导致更好的神经系统结局。尤其是不完全tSCI患者,建议尽快进行手术减压。然而,高能伤,尤其是胸廓的上层,可能太严重,不会受到手术减压的影响,这可能代表了多发性创伤患者的关键第二次打击。因此,在确定理想的手术时机之前,外科医生首先需要批判性地评估每位患者的神经功能恢复潜力.在手术干预之前必须实现循环稳定,和微创手术应该是首选。入院时应开始有创血压监测,建议将MAP维持在85至90mmHg之间,持续时间为5-7天,特别注意预防缺氧,发烧,酸中毒和深静脉血栓形成。24小时输注大剂量MPSS的作用仍然存在争议,但它可以由治疗外科医生酌情提供给急性tSCI的8小时内的成年患者作为治疗选择,特别是在非常早期的减压或不完整的tSCI的情况下。
    Acute traumatic spinal cord injury (tSCI) is a complex and heterogeneous injury, where the level of injury, injury severity, duration and degree of spinal cord compression, and blood pressure management seem to influence neurologic outcome. Although data in the literature seem to be inconsistent regarding the effectiveness of surgical decompression and spinal fixation in patients with thoracic and thoracolumbar tSCI, some single-center studies suggest that early surgical decompression may lead to a superior neurologic outcome, especially in patients with incomplete tSCI, suggesting surgical decompression to be performed as soon as possible. However, high energy injuries, especially to the upper thoracic levels, may be too severe to be influenced by surgical decompression, which may represent a critical second hit for the polytraumatized patient. Therefore, the surgeon first needs to critically evaluate the potential for neurologic recovery in each patient before determining the ideal timing of surgery. Circulatory stabilization must be achieved before surgical intervention, and minimally invasive procedures should be preferred. Invasive blood pressure monitoring should be started on admission, and maintenance of a MAP between 85 and 90 mmHg is recommended for a duration of 5-7 days, with special attention to the prevention of hypoxia, fever, acidosis and deep venous thrombosis. The role of a 24-hour infusion of high-dose MPSS is still controversial, but it may be offered at the discretion of the treating surgeon to adult patients within 8 h of acute tSCI as a treatment option, especially in the case of very early decompression or incomplete tSCI.
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  • 文章类型: Journal Article
    上皮样血管瘤(EH)是一种由上皮样细胞和内皮细胞分化组成的中度局部侵袭性肿瘤,这可以发生在任何年龄,但最常见的年龄在30到40岁之间。EH在胸椎是罕见的,准确的诊断对治疗计划至关重要。我们的目的是探索胸椎EH的影像学和临床资料,以提高对这种罕见疾病的认识。
    从2018年1月1日至2023年6月30日,对胸椎肿块数据库进行了回顾性审查。确定并分析了5例经组织学证实的胸椎EH和完整的影像学检查患者。计算机断层扫描(CT)和磁共振成像(MRI)的发现由两名具有10年以上经验的放射科医生分别评估。正电子发射断层扫描(PET)/CT由两名具有至少5年经验的核医学诊断技术人员进行。
    患者包括3名男性和2名女性患者,年龄为23至56岁(平均年龄为38.4±14.3岁)。所有患者均行CT检查,MRI,治疗前进行18F-FDGPET/CT检查。四名患者仅限于一个椎体受累,只有一名患者有多个椎体受累,所有的肿瘤都与附件有关,包括一个涉及后肋骨的.肿瘤的最大直径范围为2.7至4.3。
    CT,MRI,胸椎EH的18F-FDGPET/CT表现具有一定的特征性,了解这些影像学表现将有助于在手术前获得准确的诊断。
    UNASSIGNED: Epithelioid hemangioma (EH) is an intermediate locally aggressive tumor that consists of epithelioid cells and endothelial cell differentiation, which can occur at any age, but is most common between the ages of 30 and 40 years. EH in the thoracic spine is rare, and accurate diagnosis is critical to treatment planning. Our aim was to explore the imaging and clinical data of thoracic spine EH to improve the understanding of this rare disease.
    UNASSIGNED: From January 1, 2018 to June 30, 2023, a database of thoracic spine masses was retrospectively reviewed. Five patients with histologically proven thoracic spine EH and complete imaging available were identified and analyzed. Computed tomography (CT) and magnetic resonance imaging (MRI) findings were evaluated separately by two radiologists with more than 10 years of experience. Positron emission tomography (PET)/CT was conducted by two nuclear medicine diagnostic technologists with at least 5 years of experience.
    UNASSIGNED: The patients included three male and two female patients aged 23 to 56 years (mean age was 38.4 ± 14.3 years). All patients underwent CT, MRI, and 18F-FDG PET/CT examination before treatment. Four patients were limited to one vertebral involvement, only one patient had multiple vertebral involvement, and all tumors involved the accessories, including one involving the posterior ribs. The maximum diameter of the tumor ranged from 2.7 to 4.3.
    UNASSIGNED: CT, MRI, and 18F-FDG PET/CT findings of thoracic spine EH have certain characteristics, and understanding these imaging findings will help to obtain accurate diagnosis before surgery.
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  • 文章类型: Journal Article
    背景:在高频脊髓刺激中,以T9-10椎间盘间隙为目标的解剖放置基于“经验性”结果,该结果最好在T8至T10范围内广泛复制。本研究包含评估低胸廓形态的最大患者队列,旨在解决文献中缺乏MRI形态分析的问题。
    方法:本研究是对一个数据库的回顾性分析,该数据库包含101例接受永久性胸廓SCS植入治疗慢性疼痛的患者。在术前MRI成像上进行测量。测量脊髓和硬膜囊的前后(AP)和外侧尺寸。此外,还测量了背侧脑脊液厚度和桨下距离。
    结果:当按级别比较形态维度时,T9-10的背侧CSF厚度小于T7-8(p=0.018)。此外,T10-11时的硬脑膜外侧直径和脊髓直径大于T9-10,这有助于T10-11时的硬脑膜表面积更大(p=0.028)。虽然背侧脑脊液厚度的趋势随着胸部水平的降低而降低,脊髓与硬膜囊的表面积比似乎保持相对恒定。
    结论:在该队列中,慢性疼痛患者在T9-10时的背侧CSF厚度小于T7-8。更多的椭圆体,绳索,和椎管直径测量记录在胸椎脊髓的较低水平,特别是在T10-11。这可以与解剖SCS放置相关。未来的研究应基于这些解剖学考虑来评估SCS治疗疼痛的疗效。
    BACKGROUND: In high-frequency spinal cord stimulation anatomic placement targeting of the T9-10 disc space is based on \"empiric\" results that are best replicated with coverage broadly from T8 to T10. This study contains the largest cohort of patients evaluating low thoracic morphology and seeks to address the lack of MRI morphological analysis in literature.
    METHODS: This study was a retrospective review of a database of 101 consecutive patients undergoing permanent implant of thoracic SCS for chronic pain. Measurements were carried out on preoperative MRI imaging. Anteroposterior (AP) and lateral dimensions of the spinal cord as well as dural sac were measured. In addition, dorsal cerebrospinal fluid thickness and paddle depression distance were also measured.
    RESULTS: When comparing morphological dimensions by level, dorsal CSF thickness was smaller at T9-10 than T7-8 (p = 0.018). In addition, lateral dural and spinal cord diameters were larger at T10-11 than T9-10, contributing to larger dural surface area at T10-11 (p = 0.028). While trends of dorsal CSF thickness tend to decrease with lower thoracic levels, the ratio of surface area of spinal cord to dural sac appeared to remain relatively constant.
    CONCLUSIONS: Dorsal CSF thickness is smaller at T9-10 than T7-8 in chronic pain patients in this cohort. More ellipsoid, cord, and spinal canal diameter measurements were noted at lower levels of the thoracic spinal cord, particularly at T10-11. This may correlate with anatomical SCS placement. Future studies should evaluate efficacy of SCS therapy for pain based on these anatomical considerations.
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