Abstract：
BACKGROUND: Brain abscesses are uncommon but life-threatening in extremely preterm (EP, Gestational Age < 28 weeks) infants. The information of long-time follow-up is rare, but very few cases presented almost intact neural function after injury.
METHODS: We report the clinical course and the outcome of a 27-week preterm infant with multiple brain abscesses. The brain abscesses were detected by cranial magnetic resonance imaging (MRI) and were treated with surgical aspiration twice and a 7-week course of intravenous antibiotics. The patient had two episodes of seizure like activities at 8 and 11 years old respectively, whereas she had normal results of electroencephalogram (EEG). MRI showed encephalomalacia and periventricular leukomalacia. Otherwise, she had no obvious neurological deficits based on multiple physical examination and her intellectual quotient (IQ) was in normal range in the long-time follow-up.
CONCLUSIONS: Early diagnosis of brain abscesses and appropriate therapy can improve the prognosis. Furthermore, this case report provides an example of the possible neuroplasticity of brain in EP infants.
METHODS: We report the clinical course and the outcome of a 27-week preterm infant with multiple brain abscesses. The brain abscesses were detected by cranial magnetic resonance imaging (MRI) and were treated with surgical aspiration twice and a 7-week course of intravenous antibiotics. The patient had two episodes of seizure like activities at 8 and 11 years old respectively, whereas she had normal results of electroencephalogram (EEG). MRI showed encephalomalacia and periventricular leukomalacia. Otherwise, she had no obvious neurological deficits based on multiple physical examination and her intellectual quotient (IQ) was in normal range in the long-time follow-up.
CONCLUSIONS: Early diagnosis of brain abscesses and appropriate therapy can improve the prognosis. Furthermore, this case report provides an example of the possible neuroplasticity of brain in EP infants.
摘要：
背景：脑脓肿并不常见，但在极早产时会危及生命（EP，胎龄<28周)婴儿。长期随访的信息很少，但很少有病例在受伤后表现出几乎完整的神经功能。
方法：我们报告了一个27周早产儿多发性脑脓肿的临床过程和结果。通过颅骨磁共振成像（MRI）检测到脑脓肿，并进行两次手术抽吸和7周疗程的静脉抗生素治疗。患者在8岁和11岁时分别有2次癫痫样活动发作,而她的脑电图（EEG）结果正常。MRI显示脑软化和脑室周围白质软化。否则,根据多次体格检查，她没有明显的神经功能缺损，在长期随访中，她的智商（IQ）在正常范围内。
结论：脑脓肿的早期诊断和适当的治疗可改善预后。此外，本病例报告提供了EP婴儿大脑可能具有神经可塑性的一个例子.
方法：我们报告了一个27周早产儿多发性脑脓肿的临床过程和结果。通过颅骨磁共振成像（MRI）检测到脑脓肿，并进行两次手术抽吸和7周疗程的静脉抗生素治疗。患者在8岁和11岁时分别有2次癫痫样活动发作,而她的脑电图（EEG）结果正常。MRI显示脑软化和脑室周围白质软化。否则,根据多次体格检查，她没有明显的神经功能缺损，在长期随访中，她的智商（IQ）在正常范围内。
结论：脑脓肿的早期诊断和适当的治疗可改善预后。此外，本病例报告提供了EP婴儿大脑可能具有神经可塑性的一个例子.
