Abstract：
BACKGROUND: Early postnatal growth monitoring and nutrition assessment for preterm infants is a public health and clinical concern. We aimed to establish a set of postnatal growth monitoring curves of preterm infants to better help clinicians make in-hospital and post-discharge nutrition plan of these vulnerable infants.
METHODS: We collected weight, length and head circumference data from a nationwide survey in China between 2015 and 2018. Polynomial regression and the modified LMS methods were employed to construct the smoothed weight, length and head circumference growth curves.
RESULTS: We established the P3, P10, P25, P50, P75, P90, P97 reference curves of weight, length and head circumference that allowed for continuous use from 24 weeks of preterm birth to 50 weeks and developed a set of user-friendly growth monitoring charts. We estimated approximate ranges of weight gain per day and length and head circumference gains per week.
CONCLUSIONS: Our established growth monitoring curves, which can be used continuously without correcting gestational age from 24 weeks of preterm birth to 50 weeks, may be useful for assessment of postnatal growth trajectories, definition of intrauterine growth retardation at birth, and classification of early nutrition status for preterm infants.
METHODS: We collected weight, length and head circumference data from a nationwide survey in China between 2015 and 2018. Polynomial regression and the modified LMS methods were employed to construct the smoothed weight, length and head circumference growth curves.
RESULTS: We established the P3, P10, P25, P50, P75, P90, P97 reference curves of weight, length and head circumference that allowed for continuous use from 24 weeks of preterm birth to 50 weeks and developed a set of user-friendly growth monitoring charts. We estimated approximate ranges of weight gain per day and length and head circumference gains per week.
CONCLUSIONS: Our established growth monitoring curves, which can be used continuously without correcting gestational age from 24 weeks of preterm birth to 50 weeks, may be useful for assessment of postnatal growth trajectories, definition of intrauterine growth retardation at birth, and classification of early nutrition status for preterm infants.
摘要：
背景：早产儿出生后早期生长监测和营养评估是公共卫生和临床关注的问题。我们旨在建立一组早产儿的出生后生长监测曲线，以更好地帮助临床医生制定这些脆弱婴儿的住院和出院后营养计划。
方法：我们收集了体重，2015年至2018年中国全国调查的身长和头围数据。采用多项式回归和改进的LMS方法构建平滑权重，长度和头围生长曲线。
结果：我们建立了P3、P10、P25、P50、P75、P90、P97的体重参考曲线，长度和头围允许从早产24周到50周连续使用，并开发了一组用户友好的生长监测图表。我们估计了每天体重增加以及每周长度和头围增加的大致范围。
结论：我们建立的生长监测曲线，可以连续使用，而无需将胎龄从早产24周纠正为50周，可能有助于评估出生后的生长轨迹，出生时宫内发育迟缓的定义，早产儿早期营养状况的分类。
方法：我们收集了体重，2015年至2018年中国全国调查的身长和头围数据。采用多项式回归和改进的LMS方法构建平滑权重，长度和头围生长曲线。
结果：我们建立了P3、P10、P25、P50、P75、P90、P97的体重参考曲线，长度和头围允许从早产24周到50周连续使用，并开发了一组用户友好的生长监测图表。我们估计了每天体重增加以及每周长度和头围增加的大致范围。
结论：我们建立的生长监测曲线，可以连续使用，而无需将胎龄从早产24周纠正为50周，可能有助于评估出生后的生长轨迹，出生时宫内发育迟缓的定义，早产儿早期营养状况的分类。
