Abstract：
Laser treatment has offered a relatively nonsurgical alternative for eye, life, and vision-sparing treatment of malignant melanoma of the choroid. Historically, the most commonly used forms of lasers were xenon-arc, argon laser, krypton laser, and the more recent transpupillary thermotherapy (TTT) and photodynamic therapy (PDT). Melanomas selected for laser treatment tend to be smaller and visibly accessible, which means these tumors are usually located in the posterior choroid. Laser treatments have been associated with both local tumor destruction and side effects. Unlike radiation therapy, laser treatment has been commonly associated with retinal traction, hemorrhage, chorioretinal neovascularization, and extra scleral tumor extension, as well as higher rates of local treatment failure. In addition, however, laser-treatment has been successfully used to treat tumor-related retinal detachments, radiation retinopathy, and neovascular glaucoma. We review the world\'s experience of ophthalmic laser treatment for choroidal melanoma, offer safety and efficacy guidelines, as well as a comparison of laser treatment to radiation therapy outcomes.
摘要：
激光治疗为眼睛提供了相对非手术的选择，生活,和保留视力的治疗脉络膜恶性黑色素瘤。历史上,最常用的激光形式是氙弧，氩激光,氪激光,以及最近的经瞳孔热疗（TTT）和光动力疗法（PDT）。选择激光治疗的黑色素瘤往往较小，可见，这意味着这些肿瘤通常位于脉络膜后部。激光治疗与局部肿瘤破坏和副作用有关。与放射治疗不同,激光治疗通常与视网膜牵引有关，出血,脉络膜视网膜新生血管,和额外的巩膜肿瘤延伸，以及较高的局部治疗失败率。此外,然而,激光治疗已成功用于治疗肿瘤相关的视网膜脱离，放射性视网膜病变,和新生血管性青光眼。我们回顾了脉络膜黑色素瘤眼科激光治疗的世界经验，提供安全性和有效性指南，以及激光治疗与放射治疗结果的比较。
