Abstract：
BACKGROUND: Mondor disease is superficial thrombophlebitis of the thoracoabdominal wall, mid-upper arm, and penis. Although it is usually a benign disease requiring no specific treatment, little is known about this disease owing to its rarity.
OBJECTIVE: The aim of this retrospective observational study was to investigate the epidemiology and prognosis of Mondor disease.
METHODS: We conducted a single-center observational study of patients with Mondor disease. Patients who received a diagnosis of Mondor disease between 2015 and 2020 were analyzed. The patients\' medical records were manually reviewed to obtain the following variables: date of diagnosis, patient\'s age, sex, department of diagnosing physicians, underlying diseases, medications, surgery, and time until resolution of the lesion. We also reviewed the 1-year mortality, 1-year occurrence of malignancy, and recurrence of Mondor disease.
RESULTS: 20 patients were included in the study. The age of the patients ranged from 7 to 83 years, with a median of 47.5 years. Most of the patients presented with thoracoabdominal wall lesions. The underlying conditions included skin diseases, surgical procedures, breast cancer, smoking, and collagenous diseases, although more than half of the patients did not have plausible predisposing factors. About three-quarters of the patients saw a spontaneous resolution of the lesions within 4 weeks without medical or surgical treatments.
CONCLUSIONS: Considering the good prognosis of this disease, it is essential to avoid unnecessary invasive tests or treatment once the diagnosis is confirmed.
OBJECTIVE: The aim of this retrospective observational study was to investigate the epidemiology and prognosis of Mondor disease.
METHODS: We conducted a single-center observational study of patients with Mondor disease. Patients who received a diagnosis of Mondor disease between 2015 and 2020 were analyzed. The patients\' medical records were manually reviewed to obtain the following variables: date of diagnosis, patient\'s age, sex, department of diagnosing physicians, underlying diseases, medications, surgery, and time until resolution of the lesion. We also reviewed the 1-year mortality, 1-year occurrence of malignancy, and recurrence of Mondor disease.
RESULTS: 20 patients were included in the study. The age of the patients ranged from 7 to 83 years, with a median of 47.5 years. Most of the patients presented with thoracoabdominal wall lesions. The underlying conditions included skin diseases, surgical procedures, breast cancer, smoking, and collagenous diseases, although more than half of the patients did not have plausible predisposing factors. About three-quarters of the patients saw a spontaneous resolution of the lesions within 4 weeks without medical or surgical treatments.
CONCLUSIONS: Considering the good prognosis of this disease, it is essential to avoid unnecessary invasive tests or treatment once the diagnosis is confirmed.
摘要：
背景：Mondor病是胸腹壁浅表血栓性静脉炎，中上臂,和阴茎。虽然它通常是一种不需要特殊治疗的良性疾病，由于这种疾病的稀有性，人们对它知之甚少。
目的：这项回顾性观察研究的目的是调查Mondor病的流行病学和预后。
方法：我们对Mondor病患者进行了一项单中心观察性研究。分析了在2015年至2020年之间诊断为Mondor病的患者。对患者的医疗记录进行了手动审查，以获得以下变量：诊断日期，病人的年龄，性别,诊断医师部门，潜在的疾病，药物,手术,以及直到病变消退的时间。我们还回顾了1年死亡率，1年恶性肿瘤的发生，和Mondor病的复发。
结果：20例患者纳入研究。患者的年龄从7岁到83岁，中位数为47.5岁。大多数患者表现为胸腹壁病变。潜在的疾病包括皮肤病，外科手术,乳腺癌,吸烟,和胶原性疾病，尽管超过一半的患者没有合理的诱发因素。大约四分之三的患者在没有药物或手术治疗的情况下在4周内看到了病变的自发消退。
结论：考虑到本病的良好预后，一旦确诊，避免不必要的侵入性检查或治疗是至关重要的。
目的：这项回顾性观察研究的目的是调查Mondor病的流行病学和预后。
方法：我们对Mondor病患者进行了一项单中心观察性研究。分析了在2015年至2020年之间诊断为Mondor病的患者。对患者的医疗记录进行了手动审查，以获得以下变量：诊断日期，病人的年龄，性别,诊断医师部门，潜在的疾病，药物,手术,以及直到病变消退的时间。我们还回顾了1年死亡率，1年恶性肿瘤的发生，和Mondor病的复发。
结果：20例患者纳入研究。患者的年龄从7岁到83岁，中位数为47.5岁。大多数患者表现为胸腹壁病变。潜在的疾病包括皮肤病，外科手术,乳腺癌,吸烟,和胶原性疾病，尽管超过一半的患者没有合理的诱发因素。大约四分之三的患者在没有药物或手术治疗的情况下在4周内看到了病变的自发消退。
结论：考虑到本病的良好预后，一旦确诊，避免不必要的侵入性检查或治疗是至关重要的。
