Abstract：
From February to May 2021, four nonmigratory rams from the Radium-Stoddart bighorn sheep (BHS; Ovis canadensis) herd in the Rocky Mountains of southeastern British Columbia, Canada, died from infection with the giant liver fluke, Fascioloides magna. Affected animals were emaciated, weak, and lethargic or were found dead. Gross lesions, histopathology, and parasite burdens were consistent with those reported in experimentally infected BHS, domestic sheep, and other aberrant hosts. Although BHS range does not typically overlap with fluke-contaminated aquatic habitats, the change in migratory behavior recently observed in some Radium-Stoddart rams may have exposed the affected animals to F. magna. We describe clinical signs and gross and histopathologic findings of hepatobiliary trematodiasis associated with F. magna in free-ranging BHS. From experimental data and our findings, giant liver fluke is pathogenic and is a threat to the conservation of the Radium-Stoddart BHS herd and other BHS herds in endemic F. magna regions.
摘要：
从2021年2月到2021年5月，不列颠哥伦比亚省东南部落基山脉的Radium-Stoddart大角羊（BHS；Oviscanadensis）的四只非迁徙公羊，加拿大,死于感染巨大的肝吸虫,法西洛德·麦格纳。受影响的动物消瘦，弱,昏昏欲睡或被发现死亡。大体病变,组织病理学,寄生虫负担与实验感染的BHS报告一致，家养绵羊,和其他异常宿主。尽管BHS范围通常不会与受吸虫污染的水生栖息地重叠，最近在一些镭-斯托达特公羊中观察到的迁徙行为变化可能使受影响的动物暴露于F.magna。我们描述了在自由范围的BHS中与F.magna相关的肝胆吸虫病的临床体征以及总体和组织病理学发现。根据实验数据和我们的发现，巨大的肝吸虫具有致病性，对地方性F.magna地区的Radium-StoddartBHS牛群和其他BHS牛群的保护构成威胁。
