关键词: Anti-Allergic Agents Mometasone Furoate Quail Seasonal Allergic Rhinitis

Mesh : Humans Rhinitis, Allergic, Seasonal / drug therapy Nasal Sprays Zinc / therapeutic use Pregnadienediols / adverse effects Egg Hypersensitivity / drug therapy Mometasone Furoate Anti-Allergic Agents / adverse effects Administration, Intranasal Treatment Outcome Double-Blind Method

来  源:   DOI:10.1017/S0022215122001219

Abstract:
OBJECTIVE: Because most available treatments for managing seasonal allergic rhinitis show some side effects without reducing recurrence, natural anti-allergic products could represent an interesting treatment addition. This study aimed to analyse the efficacy and tolerance of quail egg as adjunctive therapy in seasonal allergic rhinitis.
METHODS: In a Consolidated Standards of Reporting Trials compliant framework, patients with seasonal allergic rhinitis were prospectively randomised to receive mometasone nasal spray for four weeks or the same topical corticosteroid therapy plus commercially available oral quail egg and zinc tablets.
RESULTS: Forty patients were enrolled. The mometasone + quail egg and zinc tablets group showed a greater reduction in nasal itching, sneezing and total nasal symptom scores than the mometasone nasal spray only group. A higher proportion of participants in the mometasone + quail egg and zinc tablets group had good rhinitis control than in the mometasone nasal spray only group, with no need for rescue medications.
CONCLUSIONS: Despite the need for a further larger study, quail egg preliminarily appears to be an effective adjunct to topical steroid therapy in seasonal allergic rhinitis.
摘要:
目的:因为大多数可用于治疗季节性过敏性鼻炎的治疗方法都显示出一些副作用而不减少复发,天然抗过敏产品可能是一种有趣的治疗方法。本研究旨在分析鹌鹑蛋辅助治疗季节性变应性鼻炎的疗效和耐受性。
方法:在符合合并报告标准的试验框架中,季节性过敏性鼻炎患者被随机分组,接受莫米松鼻喷雾剂治疗4周,或接受相同的局部皮质类固醇治疗加市售口服鹌鹑蛋和锌片.
结果:纳入40例患者。莫米松+鹌鹑蛋和锌片组鼻痒减轻幅度较大,喷嚏和鼻部症状总评分优于莫米松鼻喷剂组。莫米松+鹌鹑蛋和锌片组的参与者比例高于仅莫米松鼻喷雾剂组的参与者,不需要救护药物.
结论:尽管需要进一步的更大规模的研究,鹌鹑蛋初步看来是季节性过敏性鼻炎局部类固醇治疗的有效辅助手段。
公众号