UNASSIGNED: Between August 2013 and December 2014, cases (cryptogenic cirrhosis) and controls (HBV/HCV cirrhosis) above 40 years of age were prospectively recruited and assessed for the cause and prevalence of risk factors for NAFLD.
UNASSIGNED: One hundred eighteen cases (male-74%; age 55 (40-74) years; median (range); Child\'s class A:B:C-46:38:16) and 59 controls (male-80%; age 55.5 (40-69) years; Child\'s class A:B:C-56:30:14) were enrolled. Obesity (53% v/s 39%, P-0.081), diabetes mellitus (DM) (52% v/s 27%; P-0.002), family history of DM (30% v/s 13%; P-0.016), family history of Obesity (21% v/s 3.5%; P-0.002) and metabolic syndrome (65% v/s 44%; P-0.01) were more among cases than controls. Lifetime weight as obese was also longer in cases than in controls (5.9 ± 6.2 years v/s 3.2 ± 5.1 years, P-0.002). On subgroup analysis, in elderly age group, DM (55% v/s 17%, P-0.006), family history of DM (40% v/s 11%, P-0.025), metabolic syndrome (76% v/s 44%, P-0.017) and family history of obesity (19% v/s 0, P-0.047) were more common in cases as compared to controls, where as in the middle-age group, family history of obesity was the only significant factor (22% v/s 5%, P-0.025). Lifetime weight as obese was longer in cases than controls in both middle and elderly age groups.
UNASSIGNED: Among middle-aged and elderly patients with cirrhosis, there was a higher prevalence of risk factors for NAFLD in those with cryptogenic cirrhosis, compared to those with HBV or HCV cirrhosis.
UNASSIGNED:在2013年8月至2014年12月之间,前瞻性招募了40岁以上的病例(隐源性肝硬化)和对照(HBV/HCV肝硬化),并评估了NAFLD的病因和患病率。
UNASSIGNED:纳入118例(男性-74%;年龄55(40-74)岁;中位数(范围);儿童A级:B:C-46:38:16)和59名对照(男性-80%;年龄55.5(40-69)岁;儿童A级:B:C-56:30:14)。
未经证实:在中老年肝硬化患者中,