关键词: Laryngeal leukoplakia Low-temperature plasma radiofrequency ablation Wound healing

Mesh : Catheter Ablation Humans Laryngeal Diseases / surgery Leukoplakia / surgery Temperature Vocal Cords Wound Healing

来  源:   DOI:10.1080/00016489.2022.2063377

Abstract:
UNASSIGNED: Low-temperature plasma ablation (LTPA) is an emerging technique for laryngeal leukoplakia (LL).
UNASSIGNED: To initially observe the healing process of trauma after LTPA for LL.
UNASSIGNED: Seventeen patients who underwent LTPA for LL were collected, and the degrees of wound healing were analyzed.
UNASSIGNED: Only 1 patient in who dysbiosis of the pharyngeal flora was induced by self-administered hormone nebulization treatment during the follow-up period. In the remaining patients, the wound healing was characterized by a crater-shaped defect on the vocal folds surface with pseudo-membranes, congestion, and mild edema on postoperative day 1. These symptoms became worse on postoperative day 7. On postoperative day 15, the pseudo-membrane was fully formed and some patients had granulomatous swelling of the vocal cords. These symptoms became better and better on postoperative day 30 and day 45. On postoperative day 60, the mucosa of the vocal folds had essentially returned to normal. On postoperative day 90, the vocal folds morphology and function had recovered well.
UNASSIGNED: It takes 2-3 months for the wound to heal completely after LTPA for LL.
UNASSIGNED: A proper understanding of the wound healing process can reduce unnecessary surgical and pharmacologic interventions and avoid excessive treatment.
摘要:
UNASSIGNED:低温等离子消融(LTPA)是一种用于喉白斑(LL)的新兴技术。
UNASSIGNED:初步观察LTPA治疗LL后创伤的愈合过程。
未经证实:收集了17名接受LTPA治疗的患者,并对创面愈合程度进行分析。
UNASSIGNED:在随访期间,只有1例患者通过自我给药的激素雾化治疗诱导了咽部菌群失调。在剩下的病人中,伤口愈合的特点是声带表面有一个火山口状的缺损,假膜,拥塞,术后第1天轻度水肿。这些症状在术后第7天恶化。术后第15天,假膜完全形成,部分患者声带肉芽肿性肿胀。这些症状在术后第30天和第45天变得越来越好。术后第60天,声带粘膜基本恢复正常。术后第90天,声带形态和功能恢复良好。
UNASSIGNED:在进行LL的LTPA后,伤口需要2-3个月才能完全愈合。
UNASSIGNED:对伤口愈合过程的正确理解可以减少不必要的手术和药物干预,避免过度治疗。
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