PDF(Pubmed)
Abstract：
The COVID-19 pandemic has tremendously increased the production and sales of disinfectants. This study aimed to systematically review and analyze the efficacy and safety of chlorine dioxide as a disinfectant. The literature relating to the use of chlorine dioxide as a disinfectant was systematically reviewed in January 2021 using databases such as PubMed, Science Direct, and Google Scholar. Inclusion criteria were studies that investigated the use of chlorine dioxide to assess the efficacy, safety, and impact of chlorine dioxide as a disinfectant. Out of the 33 included studies, 14 studies focused on the disinfectant efficacy of chlorine dioxide, 8 studies expounded on the safety and toxicity in humans and animals, and 15 studies discussed the impact, such as water treatment disinfection using chlorine dioxide. Chlorine dioxide is a safe and effective disinfectant, even at concentrations as low as 20 to 30 mg/L. Moreover, the efficacy of chlorine dioxide is mostly independent of pH. Chlorine dioxide can be effectively used to disinfect drinking water without much alteration of palatability and can also be used to destroy pathogenic microbes, including viruses, bacteria, and fungi from vegetables and fruits. Our review confirms that chlorine dioxide is effective against the resistant Mycobacterium, H1N1, and other influenza viruses. Studies generally support the use of chlorine dioxide as a disinfectant. The concentration deemed safe for usage still needs to be determined on a case-by-case basis.
摘要：
COVID-19大流行极大地增加了消毒剂的生产和销售。本研究旨在系统评价和分析二氧化氯作为消毒剂的有效性和安全性。2021年1月，使用PubMed，科学直接，谷歌学者。纳入标准是调查使用二氧化氯来评估疗效的研究，安全,以及二氧化氯作为消毒剂的影响。在纳入的33项研究中，14项研究集中在二氧化氯的消毒剂功效上，8项研究阐述了人类和动物的安全性和毒性，15项研究讨论了这种影响，如水处理消毒使用二氧化氯。二氧化氯是一种安全有效的消毒剂,即使浓度低至20至30mg/L。此外，二氧化氯的功效主要与pH无关。二氧化氯可有效用于饮用水消毒，而不会改变适口性，也可用于破坏病原微生物，包括病毒,细菌,以及蔬菜和水果中的真菌。我们的审查证实，二氧化氯对耐药分枝杆菌有效，H1N1和其他流感病毒。研究通常支持使用二氧化氯作为消毒剂。认为使用安全的浓度仍然需要根据具体情况确定。
