Abstract：
BACKGROUND: Local tumescent anesthesia relieves postoperative pain.
OBJECTIVE: The objective of the study was to compare the effect of injecting a tumescent solution with/without ropivacaine on postoperative pain.
METHODS: A randomized, double-blind control study was conducted in 314 patients who underwent first follicular unit excision after obtaining informed consent and ethics committee approval. The patients were randomly divided into three groups: intra-groups (group 1, injected with tumescent solution with ropivacaine; group 2, without ropivacaine) and inter-group (group 3, right-head/left-head side with/without ropivacaine). Postoperative pain was recorded using the 5-point Wong-Baker Faces Pain Scale. No preoperative analgesic was administered to any patient. The survival rate of hair follicles was measured using dermoscopy during follow-up. Data were statistically analyzed.
RESULTS: Of the 314 patients included in the study, 166 were men and 148 were women with a mean age of 32.15 ± 4.58 (range, 25-45) years. Postoperative pain with ropivacaine was significantly more relieved compared with that without ropivacaine in both groups (p < 0.05). There was no significant difference between sex and survival rate of hair follicles in the intra- or inter-group.
CONCLUSIONS: A tumescent solution with ropivacaine has proven to relieve postoperative pain and is a safe and valuable form of local anesthesia in follicular unit excision.
OBJECTIVE: The objective of the study was to compare the effect of injecting a tumescent solution with/without ropivacaine on postoperative pain.
METHODS: A randomized, double-blind control study was conducted in 314 patients who underwent first follicular unit excision after obtaining informed consent and ethics committee approval. The patients were randomly divided into three groups: intra-groups (group 1, injected with tumescent solution with ropivacaine; group 2, without ropivacaine) and inter-group (group 3, right-head/left-head side with/without ropivacaine). Postoperative pain was recorded using the 5-point Wong-Baker Faces Pain Scale. No preoperative analgesic was administered to any patient. The survival rate of hair follicles was measured using dermoscopy during follow-up. Data were statistically analyzed.
RESULTS: Of the 314 patients included in the study, 166 were men and 148 were women with a mean age of 32.15 ± 4.58 (range, 25-45) years. Postoperative pain with ropivacaine was significantly more relieved compared with that without ropivacaine in both groups (p < 0.05). There was no significant difference between sex and survival rate of hair follicles in the intra- or inter-group.
CONCLUSIONS: A tumescent solution with ropivacaine has proven to relieve postoperative pain and is a safe and valuable form of local anesthesia in follicular unit excision.
摘要：
背景：局部肿胀麻醉可缓解术后疼痛。
目的：本研究的目的是比较注射含/不含罗哌卡因的肿胀溶液对术后疼痛的影响。
方法：随机，我们在获得知情同意和伦理委员会批准后接受首次卵泡单位切除的314例患者中进行了双盲对照研究.将患者随机分为三组：组内（第1组，注射罗哌卡因肿胀溶液；第2组，不注射罗哌卡因）和组间（第3组，右头/左头侧有/没有罗哌卡因）。使用5分Wong-Baker面部疼痛量表记录术后疼痛。未对任何患者进行术前镇痛。在随访期间使用皮肤镜测量毛囊的存活率。对数据进行统计分析。
结果：在纳入研究的314名患者中，男性166人,女性148人,平均年龄32.15±4.58(范围,25-45）年。两组使用罗哌卡因的术后疼痛均明显优于不使用罗哌卡因的术后疼痛（p<0.05）。在组内或组间，性别和毛囊的存活率之间没有显着差异。
结论：使用罗哌卡因的肿胀溶液已被证明可以缓解术后疼痛，并且是一种安全且有价值的局部麻醉形式。
目的：本研究的目的是比较注射含/不含罗哌卡因的肿胀溶液对术后疼痛的影响。
方法：随机，我们在获得知情同意和伦理委员会批准后接受首次卵泡单位切除的314例患者中进行了双盲对照研究.将患者随机分为三组：组内（第1组，注射罗哌卡因肿胀溶液；第2组，不注射罗哌卡因）和组间（第3组，右头/左头侧有/没有罗哌卡因）。使用5分Wong-Baker面部疼痛量表记录术后疼痛。未对任何患者进行术前镇痛。在随访期间使用皮肤镜测量毛囊的存活率。对数据进行统计分析。
结果：在纳入研究的314名患者中，男性166人,女性148人,平均年龄32.15±4.58(范围,25-45）年。两组使用罗哌卡因的术后疼痛均明显优于不使用罗哌卡因的术后疼痛（p<0.05）。在组内或组间，性别和毛囊的存活率之间没有显着差异。
结论：使用罗哌卡因的肿胀溶液已被证明可以缓解术后疼痛，并且是一种安全且有价值的局部麻醉形式。
