Abstract：
Severe fever with thrombocytopenia syndrome (SFTS) is an infection mediated by ticks and has been reported to have a high mortality rate in Japan. At our hospital, we reported three cases of SFTS with relatively positive outcomes. We reviewed reports of SFTS cases in Japan to clarify the current state of the disease in Japan, the treatment provided, and its outcome. The Ichushi Web was searched for literature using the following terms as keywords: \"SFTS\" or \"severe fever with thrombocytopenia syndrome\". Overall, 174 cases were collected and reviewed. The mean age of patients was 70.69 years old, and the mortality rate was 35%. The dead group was significantly older (p < 0.001) than the alive group, had a significantly shorter period from symptom onset to hospital admission, and experienced significantly more hemorrhage-related and neurological symptoms. Further, the most frequently provided treatment methods were adrenocorticosteroids, antibiotics, and conservative treatment. The low recognition rate of SFTS in Japan might lead to a misdiagnosis or delay in diagnosis and treatment, especially in mild to moderate cases. Medical professionals and citizens who live in areas inhabited by ticks need to be informed about SFTS to appropriately diagnose and manage SFTS cases in Japan in the future.
摘要：
严重发热伴血小板减少综合征（SFTS）是由蜱介导的感染，据报道在日本具有很高的死亡率。在我们的医院,我们报告了3例SFTS,结果相对积极.我们回顾了日本SFTS病例的报告，以澄清日本的疾病现状，所提供的治疗,和它的结果。使用以下术语作为关键词搜索IchushiWeb的文献：\"SFTS\"或\"严重发热伴血小板减少综合征\"。总的来说,收集并审查了174例病例。患者平均年龄为70.69岁,死亡率为35%。死亡组比存活组明显年龄大(p<0.001),从症状发作到入院的时间明显较短，并经历了明显更多的出血相关和神经系统症状。Further,最常提供的治疗方法是肾上腺皮质激素，抗生素,保守治疗。日本的SFTS识别率较低，可能导致误诊或延误诊治，特别是在轻度到中度的情况下。居住在蜱虫居住地区的医疗专业人员和公民需要了解SFTS，以便将来在日本适当诊断和管理SFTS病例。
