Abstract：
BACKGROUND: The choice of surgical strategy for patients with rectal gastrointestinal stromal tumor (GIST) remains controversial. This study aims to address whether the surgical procedure [local excision (LE) vs. radical excision (RE)] influences the survival outcomes.
METHODS: The information of the patients recruited in this study was obtained from the Surveillance, Epidemiology, and End Results (SEER) database. A survival curve was used to evaluate the differences in cancer-specific survival (CSS).
RESULTS: No significant difference was detected in the CSS between the LE and RE groups. Also, no significant differences were observed in the CSS between the two groups with respect to different T classification, N classification, tumor differentiation, tumor size, regional LN surgery, age, gender, race, chemotherapy, and radiotherapy. The T classification and age were independent prognostic factors in rectal GIST patients.
CONCLUSIONS: LE and RE have similar survival time after surgery, and LE could be considered as an effective surgical approach for rectal GIST.
METHODS: The information of the patients recruited in this study was obtained from the Surveillance, Epidemiology, and End Results (SEER) database. A survival curve was used to evaluate the differences in cancer-specific survival (CSS).
RESULTS: No significant difference was detected in the CSS between the LE and RE groups. Also, no significant differences were observed in the CSS between the two groups with respect to different T classification, N classification, tumor differentiation, tumor size, regional LN surgery, age, gender, race, chemotherapy, and radiotherapy. The T classification and age were independent prognostic factors in rectal GIST patients.
CONCLUSIONS: LE and RE have similar survival time after surgery, and LE could be considered as an effective surgical approach for rectal GIST.
摘要：
背景：直肠胃肠道间质瘤（GIST）患者的手术策略选择仍存在争议。本研究旨在探讨外科手术[局部切除术(LE)与根治性切除术(RE)]影响生存结果。
方法：本研究招募的患者的信息来自监测，流行病学,和结束结果(SEER)数据库。使用存活曲线来评估癌症特异性存活期(CSS)的差异。
结果：LE组和RE组的CSS没有检测到显著差异。此外，在不同的T分类方面，两组之间的CSS没有观察到显著差异，N分类，肿瘤分化，肿瘤大小,区域LN手术，年龄,性别,种族,化疗,和放射治疗。T分型和年龄是影响直肠GIST患者预后的独立因素。
结论：LE和RE术后生存时间相似，LE可以被认为是治疗直肠GIST的有效手术方法。
方法：本研究招募的患者的信息来自监测，流行病学,和结束结果(SEER)数据库。使用存活曲线来评估癌症特异性存活期(CSS)的差异。
结果：LE组和RE组的CSS没有检测到显著差异。此外，在不同的T分类方面，两组之间的CSS没有观察到显著差异，N分类，肿瘤分化，肿瘤大小,区域LN手术，年龄,性别,种族,化疗,和放射治疗。T分型和年龄是影响直肠GIST患者预后的独立因素。
结论：LE和RE术后生存时间相似，LE可以被认为是治疗直肠GIST的有效手术方法。
