%0 Journal Article
%T Survival outcome of local vs. radical excision in rectal gastrointestinal stromal tumor: a SEER database analysis.
%A Wei J
%A Zhong J
%A Chen Z
%A Huang Q
%A Wei F
%A Wang Q
%A Cao J
%A Wei J
%A Zhong J
%A Chen Z
%A Huang Q
%A Wei F
%A Wang Q
%A Cao J
%J BMC Surg
%V 22
%N 1
%D Jan 2022 22
%M 35065645
%F 2.03
%R 10.1186/s12893-022-01485-3
%X <B>BACKGROUND: </B>The choice of surgical strategy for patients with rectal gastrointestinal stromal tumor (GIST) remains controversial. This study aims to address whether the surgical procedure [local excision (LE) vs. radical excision (RE)] influences the survival outcomes.<BR><B>METHODS: </B>The information of the patients recruited in this study was obtained from the Surveillance, Epidemiology, and End Results (SEER) database. A survival curve was used to evaluate the differences in cancer-specific survival (CSS).<BR><B>RESULTS: </B>No significant difference was detected in the CSS between the LE and RE groups. Also, no significant differences were observed in the CSS between the two groups with respect to different T classification, N classification, tumor differentiation, tumor size, regional LN surgery, age, gender, race, chemotherapy, and radiotherapy. The T classification and age were independent prognostic factors in rectal GIST patients.<BR><B>CONCLUSIONS: </B>LE and RE have similar survival time after surgery, and LE could be considered as an effective surgical approach for rectal GIST.