PDF(Pubmed)
Abstract：
To make maps from airborne odours requires dynamic respiratory patterns. I propose that this constraint explains the modulation of memory by nasal respiration in mammals, including murine rodents (e.g. laboratory mouse, laboratory rat) and humans. My prior theories of limbic system evolution offer a framework to understand why this occurs. The answer begins with the evolution of nasal respiration in Devonian lobe-finned fishes. This evolutionary innovation led to adaptive radiations in chemosensory systems, including the emergence of the vomeronasal system and a specialization of the main olfactory system for spatial orientation. As mammals continued to radiate into environments hostile to spatial olfaction (air, water), there was a loss of hippocampal structure and function in lineages that evolved sensory modalities adapted to these new environments. Hence the independent evolution of echolocation in bats and toothed whales was accompanied by a loss of hippocampal structure (whales) and an absence of hippocampal theta oscillations during navigation (bats). In conclusion, models of hippocampal function that are divorced from considerations of ecology and evolution fall short of explaining hippocampal diversity across mammals and even hippocampal function in humans. This article is part of the theme issue \'Systems neuroscience through the lens of evolutionary theory\'.
摘要：
从空气中的气味绘制地图需要动态呼吸模式。我认为这种限制解释了哺乳动物鼻呼吸对记忆的调节，包括鼠类啮齿动物(例如实验室小鼠，实验室大鼠)和人类。我先前的边缘系统进化理论提供了一个框架来理解为什么会发生这种情况。答案始于泥盆纪叶翅鱼鼻呼吸的演变。这种进化创新导致了化学感应系统中的自适应辐射，包括犁鼻系统的出现和主要嗅觉系统的空间定位的专业化。随着哺乳动物继续辐射到对空间嗅觉不利的环境中(空气，水),在进化适应这些新环境的感觉形态的谱系中，海马结构和功能丧失。因此，蝙蝠和齿鲸的回声定位的独立进化伴随着海马结构（鲸鱼）的丧失和导航过程中海马theta振荡的缺失（蝙蝠）。总之,脱离生态学和进化考虑的海马功能模型无法解释哺乳动物的海马多样性，甚至无法解释人类的海马功能。本文是“进化论视角下的系统神经科学”主题的一部分。
