Abstract：
This chapter provides a broad overview of the use of individual participant (sometimes referred to as patient) data (IPD ) within meta-analyses, the associated advantages of using IPD in meta-analysis compared to aggregate data, and when IPD should be used in meta-analysis.This chapter also outlines the steps of conducting an IPD meta-analysis, with practical guidance relating to requesting and obtaining IPD for meta-analysis. Challenges that can be associated with conducting an IPD meta-analysis are also discussed, including consideration of availability bias, when a subset of the relevant IPD is not available for meta-analysis.
摘要：
本章提供了在荟萃分析中使用个体参与者（有时称为患者）数据（IPD）的广泛概述，与汇总数据相比，在荟萃分析中使用IPD的相关优势，以及何时应在荟萃分析中使用IPD。本章还概述了进行IPD荟萃分析的步骤，与请求和获得用于荟萃分析的IPD相关的实践指导。还讨论了与进行IPD荟萃分析相关的挑战，包括考虑可用性偏差，当相关IPD的子集不可用于荟萃分析时。
