Hsp90 - 免疫蛋白复合物的结构揭示了伴侣对客户成熟状态的识别。
关键词: FKBP51 Hsp90 cryo-electron microscopy (cryo-EM) heat shock proteins immunophilins molecular chaperones p23 peptidyl-prolyl isomerase (PPIase)
Mesh : Amino Acid Sequence Binding Sites Biomarkers, Tumor / chemistry metabolism Cryoelectron Microscopy / methods HSP90 Heat-Shock Proteins / chemistry metabolism Humans Molecular Chaperones / chemistry metabolism Molecular Conformation Protein Binding Tacrolimus Binding Proteins / chemistry metabolism Tumor Protein, Translationally-Controlled 1
来 源:
DOI:10.1016/j.molcel.2021.07.023
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