转录介导的超螺旋调节基因组折叠和环形成。
关键词: STORM microscopy cohesin genome folding super-resolution microscopy supercoiling transcription
Mesh : Cell Cycle Proteins / chemistry genetics metabolism Cell Line Cell Nucleus / genetics Chondroitin Sulfate Proteoglycans / genetics metabolism Chromatin / chemistry genetics metabolism Chromosomal Proteins, Non-Histone / chemistry genetics metabolism DNA Topoisomerases, Type I / genetics metabolism DNA-Binding Proteins / genetics metabolism Female Humans Lamins / genetics metabolism RNA Polymerase II / metabolism Single Molecule Imaging / methods Transcription, Genetic / physiology Cohesins
来 源:
DOI:10.1016/j.molcel.2021.06.009
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