关键词: Carbon dioxide laser Chemoradiation Laryngeal cancer Radiotherapy Salvage surgery Transoral laser microsurgery

Mesh : Carbon Dioxide Consensus Glottis Head and Neck Neoplasms Humans Laryngeal Neoplasms / surgery Laser Therapy Lasers Microsurgery Salvage Therapy Treatment Outcome

来  源:   DOI:10.1007/s00405-021-06957-5   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
OBJECTIVE: To provide expert opinion and consensus on salvage carbon dioxide transoral laser microsurgery (CO2 TOLMS) for recurrent laryngeal squamous cell carcinoma (LSCC) after (chemo)radiotherapy [(C)RT].
METHODS: Expert members of the European Laryngological Society (ELS) Cancer and Dysplasia Committee were selected to create a dedicated panel on salvage CO2 TOLMS for LSCC. A series of statements regarding the critical aspects of decision-making were drafted, circulated, and modified or excluded in accordance with the Delphi process.
RESULTS: The expert panel reached full consensus on 19 statements through a total of three sequential evaluation rounds. These statements were focused on different aspects of salvage CO2 TOLMS, with particular attention on preoperative diagnostic work-up, treatment indications, postoperative management, complications, functional outcomes, and follow-up.
CONCLUSIONS: Management of recurrent LSCC after (C)RT is challenging and is based on the need to find a balance between oncologic and functional outcomes. Salvage CO2 TOLMS is a minimally invasive approach that can be applied to selected patients with strict and careful indications. Herein, a series of statements based on an ELS expert consensus aimed at guiding the main aspects of CO2 TOLMS for LSCC in the salvage setting is presented.
摘要:
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