{Reference Type}: Journal Article
{Title}: Salvage carbon dioxide transoral laser microsurgery for laryngeal cancer after (chemo)radiotherapy: a European Laryngological Society consensus statement.
{Author}: Piazza C;Paderno A;Sjogren EV;Bradley PJ;Eckel HE;Mäkitie A;Matar N;Paleri V;Peretti G;Puxeddu R;Quer M;Remacle M;Vander Poorten V;Vilaseca I;Simo R;
{Journal}: Eur Arch Otorhinolaryngol
{Volume}: 278
{Issue}: 11
{Year}: Nov 2021
{Factor}: 3.236
{DOI}: 10.1007/s00405-021-06957-5
{Abstract}: <B>OBJECTIVE: </B>To provide expert opinion and consensus on salvage carbon dioxide transoral laser microsurgery (CO2 TOLMS) for recurrent laryngeal squamous cell carcinoma (LSCC) after (chemo)radiotherapy [(C)RT].<BR><B>METHODS: </B>Expert members of the European Laryngological Society (ELS) Cancer and Dysplasia Committee were selected to create a dedicated panel on salvage CO2 TOLMS for LSCC. A series of statements regarding the critical aspects of decision-making were drafted, circulated, and modified or excluded in accordance with the Delphi process.<BR><B>RESULTS: </B>The expert panel reached full consensus on 19 statements through a total of three sequential evaluation rounds. These statements were focused on different aspects of salvage CO2 TOLMS, with particular attention on preoperative diagnostic work-up, treatment indications, postoperative management, complications, functional outcomes, and follow-up.<BR><B>CONCLUSIONS: </B>Management of recurrent LSCC after (C)RT is challenging and is based on the need to find a balance between oncologic and functional outcomes. Salvage CO2 TOLMS is a minimally invasive approach that can be applied to selected patients with strict and careful indications. Herein, a series of statements based on an ELS expert consensus aimed at guiding the main aspects of CO2 TOLMS for LSCC in the salvage setting is presented.