关键词: Antibacterial and cytotoxicity Cassia angustifolia Nano particles TEM Zinc

来  源:   DOI:10.1016/j.sjbs.2021.02.075   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
The plant Cassia angustifolia belongs to Saudi Arabia, which is one of the native places and now cultured throughout the global countries. Medical care in the Arab world is an essential outlet for medicinal plants, both because they are crucial elements for prophetic medicine and due to their lengthy background in the Middle East. C.angustifolia is one of the medicinal plants used in the Saudi Arabia. The usage of plant extracts for synthesizing nanoparticles is conducive to other biological material, since it avoids the lengthy phase of cell culture maintenance. Silver nanoparticles attract further attention due to their strong conductivity, stability and antimicrobial activity across different metal nanoparticles. The present study was designed in the Saudi C. angustifolia leaves with the zinc synthesis of nanoparticles and its antibacterial ability. The plant extracts of C. angustifolia was used for synthesis of zinc nanoparticles, antimicrobial activities against bacterial strains have been tested along with transmission electron microscope (TEM), UV spectroscopy and antimicrobial activities have been conducted. This study showed that silver ions may be transferred from the plant extract to silver nanoparticles. AgNPs biogenic capacity to antibacterial with lovo cell with IC50 ranged from 33.5 ± 0.2 μg/mL demonstrated strong antibacterial capacity to antibody. The overall absorption value for the extract was between 420 and 440 nm and the color transition to green was the plasma absorption of the AgNPs. TEM results was showed in 200,000 magnification. The uniqueness of the current study is that Cassia angustifolia leaf extract from Saudi Arabia was used to prepare the metallic nanoparticles. Additionally, ZnCl2 may also be used as nanoparticles of mineral salt and zinc, which, since their application has been confirmed, are antimicrobial.
摘要:
植物决明子属于沙特阿拉伯,这是一个本土的地方,现在培养了整个全球国家。阿拉伯世界的医疗保健是药用植物的重要出口,这既是因为它们是预言医学的关键因素,也是因为它们在中东的长期背景。C.angustifolia是沙特阿拉伯使用的药用植物之一。利用植物提取物合成纳米颗粒有利于其他生物材料,因为它避免了细胞培养维持的漫长阶段。银纳米粒子由于其强大的导电性而引起进一步的关注,在不同的金属纳米粒子的稳定性和抗菌活性。本研究是在沙特沙棘叶中设计的具有锌纳米颗粒的合成及其抗菌能力的研究。沙棘的植物提取物用于合成纳米锌,对细菌菌株的抗菌活性已经用透射电子显微镜(TEM)进行了测试,已经进行了UV光谱和抗微生物活性。这项研究表明,银离子可能从植物提取物转移到银纳米颗粒。AgNP对lovo细胞的抗菌生物能力的IC50范围为33.5±0.2μg/mL,证明了对抗体的强抗菌能力。提取物的总吸收值在420和440nm之间,并且向绿色的颜色转变是AgNP的血浆吸收。TEM结果显示在200,000放大倍数下。目前研究的独特之处在于,将沙特阿拉伯的决明子叶提取物用于制备金属纳米颗粒。此外,ZnCl2也可以用作无机盐和锌的纳米颗粒,which,由于他们的申请已经得到确认,是抗菌的。
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