tRNA 易位抑制剂对核糖体亚基动力学的扰动。
关键词: EF-G antibiotics rapid kinetics ribosome head domain swiveling ribosome subunit rotation translation elongation
Mesh : Anti-Bacterial Agents / pharmacology Biological Transport Cinnamates / pharmacology Escherichia coli / drug effects genetics metabolism Hygromycin B / analogs & derivatives pharmacology Kanamycin / pharmacology Kinetics Neomycin / pharmacology Paromomycin / pharmacology Peptide Elongation Factor G / genetics metabolism Protein Biosynthesis / drug effects RNA, Messenger / chemistry genetics metabolism RNA, Transfer / antagonists & inhibitors chemistry genetics metabolism Ribosome Subunits / drug effects genetics metabolism ultrastructure Spectinomycin / pharmacology Streptomycin / pharmacology Viomycin / pharmacology
来 源:
DOI:10.1261/rna.078758.121
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