关键词: gastrectomy gastric cancer greater omentum omentectomy surgery

Mesh : Adolescent Adult Aged Disease-Free Survival Female Gastrectomy / methods statistics & numerical data Humans Lymph Node Excision Male Middle Aged Neoplasm Recurrence, Local / epidemiology prevention & control Neoplasm Staging Omentum / surgery Organ Sparing Treatments / methods statistics & numerical data Prognosis Prospective Studies Randomized Controlled Trials as Topic Retrospective Studies Stomach Neoplasms / diagnosis mortality surgery Survival Rate Young Adult

来  源:   DOI:10.2217/fon-2021-0240

Abstract:
Although complete omentectomy is traditionally performed in patients with gastric cancer as part of radical gastrectomy to ensure the elimination of micrometastases, the prognostic value of omentectomy during gastrectomy remains unclear. Retrospective studies have shown that the incidence of metastases in the greater omentum is very low in T1-T3 gastric cancer. Thus radical gastrectomy with D2 lymphadenectomy and preservation of the greater omentum may be a proper curative treatment for gastric cancer patients with T1-T3 tumors. The aim of this article is to describe the design and rationale for this prospective, randomized controlled DRAGON-05 trial, conducted to evaluate the prognostic value of omentum-preserving gastrectomy for patients with T1-T3 gastric cancer. Clinical trial registration: ChiCTR2000040045 (ClinicalTrials.gov).
摘要:
尽管传统上胃癌患者作为根治性胃切除术的一部分进行完整的网膜切除术,以确保消除微转移,胃切除术中网膜切除术的预后价值尚不清楚.回顾性研究表明,在T1-T3胃癌中,大网膜转移的发生率非常低。因此,对于T1-T3肿瘤的胃癌患者,根治性胃切除术加D2淋巴结清扫术和保留大网膜可能是一种合适的治疗方法。本文的目的是描述这种前瞻性的设计和基本原理,随机对照DRAGON-05试验,进行评估保留网膜胃切除术对T1-T3胃癌患者的预后价值。临床试验注册:ChiCTR2000040045(ClinicalTrials.gov)。
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